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MedChemExpressModel (2R,5S)-Ritlecitinib -1792180-79-0

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(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC50=144.8 nM) extracted from patent US20150158864A1, example 68[1].
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(2R,5S)-Ritlecitinib

MCE China:(2R,5S)-Ritlecitinib

Brand:MedChemExpress (MCE)

Cat. No.HY-100754B

CAS:1792180-79-0

Synonyms:(2R,5S)-PF-06651600

Purity:99.77%

Storage:4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Shipping:Room temperature in continental US; may vary elsewhere.

Description:(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC50=144.8 nM) extracted from patent US20150158864A1, example 68.

IC50 & Target:JAK3 144.8 nM (IC50)

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References:

[1]. Atli Thorarensen, et al. Pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl and pyr-rolo[2,3-d]pyridinyl acrylamides. US20150158864A1.

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