Gentronix - Full Plate Ames

Ames assays are bacterial reverse mutation assays that use a variety of Salmonella (or E. coli) strains to detect a range of point mutations and have high sensitivity when used in combination. The Ames test is the most established assay for detecting direct-acting mutagens and forms a key aspect of regulatory genotoxicity testing across industries. As such, an early stage prediction of Ames test outcome is a key step in assessing the toxicological hazard of test substances during development. Gentronix offers a range of service options to meet your project requirements.

OECD 471 Ames Test Strains: TA98, TA100, TA1535, TA1537, TA102, TA97, TA97a, uvrA/pKM101, WP2 pKM101, WP2 uvrA
Metabolic activation: Typically induced rat liver S9, though other
sources are available
Test Format: Plate incorporation, pre-incubation
Typical test item requirements: 350mg
Formulation Analysis: Available upon request
Endpoint: Mutagenicity