Infors HT - Model Minifors 2 -Benchtop Bioreactors

Quickly begin your experiments
Get your experiments started quickly with minimal experience thanks to the preconfigured delivery and intuitive controls of this bench-top bioreactor. Simply connect the device, mount the vessel, connect pumps and sensors, and begin your work quickly.

Compact and easy to handle
Requiring very little space on the lab bench, this compact bench-top bioreactor is designed for optimal handling and operation. All components are easily accessible and allow for stress-free transport within the vessel holder, to and from autoclave, fitting within smaller autoclaves with only 30 cm inner diameter.

Easily automate your data management
Save time and resources by automating your data management with eve®, a web-based bioprocess platform software. Accessing your data from anywhere so you can collaborate with colleagues at different facilities, leading to faster research results. 

Culture vessels

• Available in total volumes of 1.5 L, 3 L and 6 L
• Quick and easy change between culture vessel sizes
• Rounded flat vessel bottom: Low minimum working volume, good mixing, stability with or without a vessel holder
• Safe sampling without any dead volume: INFORS HT Super Safe Sampler

Top plate

• Intelligent design for easy access to all ports
• Sufficient ports, for standard fittings and extra inlets, immersion tubes and sensors
• 4 x 7.5 mm: addition ports available for acid, base, feed & 1 free
• 4 x 10 mm: sparger, anti-foam system, temperature sensor, sampling/harvest
• Maximum 7 x 12 mm (Pg13.5): pH, pO2, exhaust gas cooler, inoculation are pre-allocated, 3 are freely available
• Convenient, tool-free cleaning and maintenance thanks to knurled screws

High-performance pumps

• 4 High-performance pumps
• Configurable operating mode: digital (fixed-speed) or analogue (variable speed)
• 3 x fix (acid, base, antifoam), 1 x variable (feed)
• Autoclavable pump heads
• Gravimetric feeding with dosing mode (requires external scale)
• Profile-based pump-speed control (with eve®)
• 2 analogue inputs / outputs to connect external pumps (version for cell cultures)

Gassing

• 2 integrated MFC for air, air/O2, or air/N2 (version for microorganisms)
• 5 integrated MFC for air, O2, N2, CO2 and head space gassing (version for cell cultures)
• Integrated pressure sensor for detecting a blocked filter
• Gassing optimised for bacteria applications and cell cultures: specific gassing rate (vvm) up to 2.0 min-1
• Multiple cascades for pO2 control by means of stirrer speed, gassing rate (“TotalFlow”) and/or gas composition (“GasMix”)

Sensors

• Robust, digital connection of pH and pO2 sensors
• Optical pO2 sensor: immediately ready for use, no polarization required
• Calibration data stored in sensor head
• Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
• Optional: biomass sensors from Optek and aquila biolabs

Operating unit

• Integrated 7" touch screen (17.8 cm)
• Simple handling through intuitive menus and practical on-screen help
• Calibration of pH, pO2 and OD sensors using simple install wizards
• Direct data export to USB drive in stand-alone operation
• Multiple display languages

eve® Bioprocess Platform Software

• Planning, controlling and analysing bioprocesses
• Integrated workflows, devices and bioprocess knowledge
• Integrates bioreactors and analytical instruments, regardless of the manufacturer
• Web-based project organisation
• Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
• Synchronisation of process-related events such as sampling or inoculation

• Vessels: 1.5 L / 3 L / 6 L
• Working volume: 0.3–1,0 L / 0.6–2.0 L / 1.1–4-0 L
• Dimensions (W x D x H): 455 mm x 375 mm x 740 mm
• Drive: Version for Microorganisms: 150 min-1 to 1600 min-1 Version for cell cultures: 24 min–1 to 600 min-1
• Temperature: Coolant temperature + 10 °C bis 60 °C
• Gassing per vessel: Version for microorganisms: 2 MFCs up to 2 min-1, version for cell cultures: 5 MFCs up to 0.15 min-1
• Pumps per vessel: 4 x configurable (fixed or variable speed) ex-works: 3 x fixed (acid, base, anti-foam), 1 x variable (feed)
• Pump performance: 0.0034 to 3,52 mL min-1 (standard), 0.017 to 16,13 mL min-1, 0.0012 to 1.12 mL min-1
• Ports per vessel: 
• 7,5 mm   4x
• 10 mm    4x
• 12 mm (Pg13,5)  max. 7x
• Connectivity: OPC UA via Ethernet
• Parallel operation via touch screen controller: 1 unit
• Sterilisation: Autoclave