Infors HT - Model Multifors 2 -Benchtop Parallel Bioreactor System

Maximum options while minimizing contamination risks
The magnetic drive system allows for maximum headplate ports and ergonomics while minimizing the contamination risk and wear on components; capable of 1600 RPM operation for extended continuous batches.

Increase productivity and minimize downtime within existing lab space
Save time, space, and resources with optimized parallel bioprocessing, operating up to 6 Multifors® bioreactor vessels from one touchscreen control. With a small footprint and robust housing, you can make the most of your bench space.

Easily scale-up your process
Be prepared to scale-up from the bench using the same sensor technologies as the larger scale bioreactors, delivering comparable data. Optional PAT tools are available to offer a straightforward way of preparing for later production at bench or pilot-scale bioreactors. 

Culture vessels

• Culture vessels are easy to exchange
• Powerful magnetic drive
• Magnetic coupling reduces the risk of contamination and simplifies handling
• Specialized stirring systems for microorganisms and cell cultures

Top plate

• Motor underneath the vessel for excellent accessibility to available ports
• Up to 13 ports for sensors (antifoam, optical density, pH, pO2, redox, conductivity, live cell density, etc.)

High-performance pumps

• Basic setup includes four precision pumps per culture vessel (option of one more)
• Autoclavable pump heads
• Gravimetric feeding (with external scale)
• Profile-based pump-speed control with eve®

Gassing

• Customer-specific gassing with up to 5 gas lines, either via a sparger or in the headspace
• Feed via rotameter or mass-flow regulator
• Cascades may be configured in serial or in parallel for controlling the pO2 via the stirrer speed, gassing rate, gas composition, etc.
• pH control with acid and CO2

Sensors

• Customers may choose from digital (Modbus) or analog sensors.
• Product calibration of the pH sensor for reliable measurements during long-running bioprocesses
• If required, additional sensors and actuators can be connected.

12" Touchscreen Controller

• Touchscreen with integrated OPC server
• Reliable measurement and setting of the bioprocess parameters and communication with eve®
• Parallel management and control of up to six devices
• Up to 24 selectable parameters, such as temperature, stirring speed, pH, pO2, anti-foaming agent, feed

eve® Bioprocess Platform Software

• Planning, controlling and analysing bioprocesses
• Integrated workflows, devices and bioprocess knowledge
• Integrates bioreactors and analytical instruments, regardless of the manufacturer
• Web-based project organisation
• Communication using the latest OPC UA (Minifors 2) or OPC XML-DA standard (Multifors 2, Labfors 5, Techfors-S, Techfors)
• Synchronisation of process-related events such as sampling or inoculation

• Vessels: 0,4 L / 0,75 L / 1,4 L
• 0,4 L / 0,7 l / 1,0 L (cell version)
• Working volume: 0,15–0,25 L / 0,18–0,5 L / 0,32–1 L
• 0,097–0,25 L / 0,15–0,5 L / 0,22–0,75 L (cell version)
• Dimensions (W x D x H): 350 mm x 520 mm x 960 mm
• Drive: Magnetic drive to 1600 min-1
• Temperature: Coolant temperature + 5 °C to 70 °C
• Gassing per vessel: Up to 4 rotameters oder MFCs up to 2 min-1 (vvm) or 0,1 min-1 (vvm) (cell version)
• Pumps per vessel: 3 fixed, 1 variable, optional 1 additional variable
• Pump performance: Depending on the design from 0,0012 mL min-1 to 3,46 mL min-1
• Ports per vessel: 
• 7 mm  4x
• 10 mm 4x
• 12 mm (Pg13,5)  max. 5x
• Connectivity: OPC XML DA via Ethernet
• Parallel operation via touch screen controller: 3 base units, resp. 6 vessels
• Sterilisation: Autoclave