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- Hichrom - Model RPB - LC Columns
Hichrom - Model RPB -LC Columns
High purity base deactivated silica. 3.5, 5 and 10μm particle sizes. Unique C8/C18 multi-alkyl phase. Excellent chromatography. Hichrom RPB is a high purity base deactivated silica which offers a unique selectivity due to the proprietary C8/C18 multi-alkyl bonding and exhaustive endcapping employed. The range includes 3.5, 5 and 10μm phases, which are suitable for LC-MS applications and preparative separations respectively.
Hichrom RPB is specifically designed for the Reversed-Phase separation of Basic molecules.
The use of organic modifiers is minimised. Residual acidic sites have been eliminated whilst monolayer coverage of the high purity silica surface has been retained to obtain optimum plate efficiency. Both octyl- and octadecylsilanes are bonded to give a material which combines the robustness of a C18 phase with the high coverage of a C8 phase.
Excellent peak shapes are obtained for basic drug molecules. In addition, acids and bases can be similarly chromatographed under suitably buffered conditions (see Figure 1).