LC-MS Spectrometry

Resolution and versatility are provided by LC-MS. It is a commonly used technique that is usually used with mass spectrometry to isolate chemicals from a sample before examination. With LC, the interaction of the compounds with the mobile and stationary phases provides the basis for the separation of the sample components, and the degree of compound separation is correlated with each molecule`s affinity for the mobile phase. Following chromatographic separations, substances are delivered into the mass spectrometer for mass analysis after eluting from the column, being desolvated into the gas phase, and being ionized at an ionization source.