MedChemExpress - Model AZD-5069 -878385-84-3
AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.MCE products for research use only. We do not sell to patients.
AZD-5069
MCE China:AZD-5069
Brand:MedChemExpress (MCE)
Cat. No.HY-19855
CAS:878385-84-3
Purity:99.91%
Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Shipping:Room temperature in continental US; may vary elsewhere.
Description:AZD-5069 is a potent CXCR2 chemokine receptor antagonist, used for caner treatment.
In Vitro:AZD-5069 (Compound 2) acts as CXCR2 antagonist by inhibition of [125I]-IL-8 binding to human CXCR2 receptors and as inhibitor of GROα-induced Ca2+ flux in human neutrophils loaded with fluo-3 dye[1].
IC50 & Target:125I-IL-8-CXCR2
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Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
References:
[1]. Norman P, et al. Evidence on the identity of the CXCR2 antagonist AZD-5069. Expert Opin Ther Pat. 2013 Jan;23(1):113-7. [Content Brief]
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