MedChemExpress - Model DNA2 inhibitor C5 -35973-25-2
DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress[1].MCE products for research use only. We do not sell to patients.
DNA2 inhibitor C5
MCE China:DNA2 inhibitor C5
Brand:MedChemExpress (MCE)
Cat. No.HY-128729
CAS:35973-25-2
Purity:98.51%
Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Shipping:Room temperature in continental US; may vary elsewhere.
Description:DNA2 inhibitor C5 is a potent, competitive and specific inhibitor of DNA2 nuclease activity with an IC50 of 20 μM. DNA2 inhibitor C5 inhibits nuclease, DNA dependent ATPase, helicase, and DNA binding activities of DNA2. DNA2 inhibitor C5 is a promising lead compound to develop sensitizers for cancer chemotherapeutics that cause replication stress.
IC50 & Target:IC50: 20 μM (DNA2 nuclease)[1] Cellular Effect Cell Line Type Value Description References
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References:
[1]. Binghui Shen, et al. Dna2 inhibitors for cancer treatment. US20170226063A1.
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