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MedChemExpressModel Mcl1-IN-11 -2042211-13-0

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Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively[1].
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MCE products for research use only. We do not sell to patients.

Mcl1-IN-11

MCE China:Mcl1-IN-11

Brand:MedChemExpress (MCE)

Cat. No.HY-100762

CAS:2042211-13-0

Storage:Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.

IC50 & Target:Ki: 0.06 (Mcl-1), 4.2 μM (Bcl-2)[1] Cellular Effect Cell Line Type Value Description References

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References:

[1]. Wang M, et al. Design, synthesis, and activity evaluation of selective inhibitors of anti-apoptotic Bcl-2 proteins: The effects on the selectivity of the P1 pockets in the active sites. Bioorg Med Chem Lett. 2016 Nov 1;26(21):5207-5211.  [Content Brief]

Brand introduction:
•   MCE (MedChemExpress) has a global exclusive compound library of more than 200 kinds, and we are committed to providing the most comprehensive range of high-quality small molecule active compounds for scientific research customers around the world;
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