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MedChemExpressModel N-Hexanoyl-L-homoserine lactone -147852-83-3

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N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). Diatoms are frequently found in association with Proteobacteria, many members of which employ cell-to-cell communication via AHLs in aquatic habitats[1].
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N-Hexanoyl-L-homoserine lactone

MCE China:N-Hexanoyl-L-homoserine lactone

Brand:MedChemExpress (MCE)

Cat. No.HY-133685

CAS:147852-83-3

Purity:98.82%

Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Shipping:Room temperature in continental US; may vary elsewhere.

Description:N-Hexanoyl-L-homoserine lactone is a short-chained N-acyl homoserine lactone (AHL). N-hexanoyl-L-homoserine lactone is also a mediator of bacterial quorum-sensing regulation. N-hexanoyl-L-homoserine lactone promotes lipid accumulation in algae. AHL is an intercellular communication signal molecule in the quorum sensing system of Gram-negative bacteria and a medium for mediating information exchange between eukaryotic plants and prokaryotic bacteria. AHL can affect bacteria activities, such as biofilm formation, pigment synthesis, and antibiotic synthesis.

In Vitro:N-hexanoyl-L-homoserine lactone (400 nM) effectively promotes the accumulation of lipid concentration in algae cells in the mixed culture system of Chlorella vulgaris and Chlamydomonas[2]. N-hexanoyl-L-homoserine lactone (72 h) is undetectable in the root system of Lotus[3]. N-hexanoyl-L-homoserine lactone (50 μM) facilitates electron utilization by cathodic homoacetogens for CO2 reduction[4].

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References:

[1]. Frederike Stock,et al. Distinctive Growth and Transcriptional Changes of the Diatom Seminavis robusta in Response to Quorum Sensing Related Compounds. Front Microbiol. 2020 Jun 9;11:1240.  [Content Brief]

[2]. Liao L, et al. Effect of the N-hexanoyl-L-homoserine Lactone on the Carbon Fixation Capacity of the Algae-Bacteria System. Int J Environ Res Public Health. 2023 Mar 13;20(6):5047.  [Content Brief]

[3]. Delalande L, et al. N-hexanoyl-L-homoserine lactone, a mediator of bacterial quorum-sensing regulation, exhibits plant-dependent stability and may be inactivated by germinating Lotus corniculatus seedlings. FEMS Microbiol Ecol. 2005 Mar 1;52(1):13-20.  [Content Brief]

[4]. Zhou M, et al. Enhanced CO2 reduction and acetate synthesis in autotrophic biocathode by N-Hexanoyl-L-homoserine lactone (C6HSL)-based quorum-sensing regulation. Sci Total Environ. 2022 Aug 25;836:155724.  [Content Brief]

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