MedChemExpress LLC (MCE)

MedChemExpressModel Rosoxacin -40034-42-2

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Rosoxacin (Acrosoxacin) is an orally active and broad-spectrum antibacterial quinolone antibiotic. Rosoxacin inhibits Gram-negative bacteria, including N. gonorrhoeae (MIC range=0.03-0.125 µg/mL).Rosoxacin can be used in studies of urinary tract infections and certain sexually transmitted diseases[1].
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Rosoxacin

MCE China:Rosoxacin

Brand:MedChemExpress (MCE)

Cat. No.HY-A0208

CAS:40034-42-2

Synonyms:Acrosoxacin

Purity:98.31%

Storage:Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year

Shipping:Room temperature in continental US; may vary elsewhere.

Description:Rosoxacin (Acrosoxacin) is an orally active and broad-spectrum antibacterial quinolone antibiotic. Rosoxacin inhibits Gram-negative bacteria, including N. gonorrhoeae (MIC range=0.03-0.125 µg/mL).Rosoxacin can be used in studies of urinary tract infections and certain sexually transmitted diseases.

In Vitro:Rosoxacin (0.03-8 µg/mL; 24 h) shows good susceptibilities to 32 strains of N. gonorrhoeae, with MIC range of 0.03-0.125 µg/mL[1]. Rosoxacin (0.03-8 µg/mL; 48 h) shows antibacterial activity to C. trachomatis (11 strains), with MICs are 5 µg/mL[1]. Rosoxacin (0.03-8 µg/mL; 6 days) shows antibacterial activity to U. urealyticum (7 strains), with MIC range of 2-8 µg/mL[1].

IC50 & Target:Quinolone

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References:

[1]. Dobson RA, et al. In vitro antimicrobial activity of rosoxacin against Neisseria gonorrhoeae, Chlamydia trachomatis, and Ureaplasma urealyticum. Antimicrob Agents Chemother. 1980 Nov;18(5):738-40.  [Content Brief]

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