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MedChemExpressModel TRAF6 peptide -852805-92-6

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TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke[1].
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TRAF6 peptide

MCE China:TRAF6 peptide

Brand:MedChemExpress (MCE)

Cat. No.HY-P3709

CAS:852805-92-6

Storage:Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping:Room temperature in continental US; may vary elsewhere.

Description:TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke.

In Vitro:TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1]. TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1].

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References:

[1]. Wooten, Marie W. Substances interfering with TRAF6-p62 interaction for inhibiting intracellular aggregate formation and methods for screening for such substances. Patent WO2005050170A2.

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