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Model 6500 Series -Accurate-Mass Quadrupole Time-of-Flight (Q-TOF) LC/MS

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The Agilent 6500 Accurate-Mass Q-TOF LC/MS systems provide superior data quality and advanced analytical capabilities for profiling, identifying, characterizing, and quantifying low molecular-weight compounds and biomolecules with confidence. These Q-TOF systems deliver exceptional MS and MS/MS analyses that support demanding applications such as proteomics, metabolomics, impurity testing, product degradation studies, forensics, food safety, and environmental analyses. The new 6540 Q-TOF delivers outstanding performance characteristics without speed related performance compromises (sensitivity, dynamic range, isotopic fidelity, mass range) associated with orbital trapping instruments.

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  • Typical mass accuracy – sub-1-ppm MS and 2-ppm MS/MS rivals or exceeds that of much more expensive FTMS and orbital trapping instruments
  • Enhanced mass resolution – up to 40,000 mass resolution capability distinguishes target analytes from interferences
  • Agilent Jet Stream technology provides 5x greater on-column sensitivity in the 6530
  • Spectral acquisition rates – up to 20 MS or 10 MS/MS spectra per second for compatibility with high-throughput, rapid-resolution chromatography such as Agilent 1290 UHPLC
  • In-spectrum dynamic range – up to 5 orders reveal trace-level targets even in the presence of vastly more abundant compounds
  • Time-of-flight mass range – m/z 20 – 20,000
  • Automated tuning that is unavailable from or unreliable on competitive instruments
  • MassHunter Workstation software takes advantage of accurate mass MS and MS/MS and high definition isotopic data to facilitate profiling, characterization, identification and quantification of compounds in complex mixtures.