Model Arthus -Artificial Human Sera (Arthus) for The Standardization of In-Vitro Allergy Diagnostics

The availability of well-defined quality controls (positive human sera) is urgently required for the development, production, evaluation, standardization and quality control of allergy in-vitro test systems. However, the availability of human control sera is severely limited. In addition, the sera from commercial serum banks (often serum pools) sometimes show fluctuating quality and are very expensive. Allergen extracts in the commercially available test systems vary in composition due to the raw material used, the manufacturing process and storage conditions .......