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- Model Maleimide - Gold Nanoparticles
Model Maleimide -Gold Nanoparticles
FromLuna Nanotech
Features: A range of available sizes: 4 to 200 nm diameter. High monodispersity (PDI < 0.1) and circularity (> 0.9). Stable in high salt conditions. Can be used to conjugate proteins and small molecules.
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- Maleimide-terminated polyethylene glycol (PEG, 5 kDa) grafting introduces a terminal Maleimide group that can be used for conjugation to Thiol-containing molecules through Maleimide chemistry.
- Methoxy-terminated PEG is used as the backfill to stabilize the particles against charge-induced aggregation.
- Nanoparticle conjugation to proteins and targeting ligands.
- Actively targeted gold conjugate nanoparticles for in vitro and in vivo studies.
- Gold nanoparticles for lateral flow and immune assays.
- Gold nanoparticle labeling probes for electron microscopy.
- Core Diameter: 4 nm – 200 nm
- Polydispersity Index (PDI): < 0.1
- Absorbance peak: 520 – 580 nm
- Maleimide is introduced at the end of 5 kDa PEG spacer
- Shelf life: > 1 year (4°C storage)
- Supplied as freeze-dried powder (NOTE: trehalose is used as cryopreservant; once product is redispersed in buffer, trehalose final concentration is 0.45% w/v)
- For long-term storage (>1 month), store the product at or below -20°C. For shorter periods (<1 month) product can be stored at 4°C or room temperature.
- Immediately before use, resuspend the nanoparticles in the indicated volume of 1X PBS or another buffer.