MedChemExpress - Model Subasumstat -1858276-04-6
Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities[1][2].MCE products for research use only. We do not sell to patients.
Subasumstat
MCE China：Subasumstat
Brand：MedChemExpress (MCE)
Cat. No.HY-111789
CAS：1858276-04-6
Synonyms：TAK-981
Purity：98.56%
Storage：Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Shipping：Room temperature in continental US; may vary elsewhere.
Description：Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.
In Vitro：Subasumstat (TAK-981) is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, activating innate effector cells and enhancing the antitumor innate immune responses[1].
In Vivo：A single sub-cutaneous injection of Subasumstat (TAK-981) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs[2].
IC50 & Target：SUMOylation[1]. Cellular Effect Cell Line Type Value Description References
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References：
[1]. Sumoylation inhibitor TAK-981.
[2]. TAK-981.
Brand introduction:
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