Sotera Health

Noxilizer (NO2 Sterilizer)

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Nitrogen Dioxide (NO2 )-based sterilization offers ultra-low temperature, minimal pressure requirements, no cytotoxic residuals, and fast cycle times.

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Attribute: Parameter Range

  • Nitrogen dioxide gas sterilant: Boiling point 21°C
  • Low sterilant concentration: 1 mg/L – 20 mg/L (less than 1%)
  • Ultra low or room temperature process: Lethality achieved at ambient temperatures (10-30°C)
  • Non-condensing gas sterilant: Greater efficacy in lumens, easier to aerate
  • Raising relative humidity reduces cycle time:
  • 70% - 80% RH provides rapid lethality
  • 40% RH requires longer exposure time
  • Short exposure: Typically less than one hour
  • Low sterilant residuals: Residuals often not measureable, no increase in cytotoxicity observed

We are over 1,600 engineers, scientists, safety specialists and solution providers focused on eliminating threats to the health of humanity. We have global breadth and more than 90 years of deep expertise across Gamma, EO, E-Beam and X-ray sterilization. Our operations span 48 facilities in 13 countries to ensure we are the “point of safe” for our customers. Safeguarding Global Health™ – with every product we sterilize.