COMET - Partial Pressure Oxygen Measurement System

We expect that the measurement of oxygen in the cells will enable doctors to guide the many interventions to ensure oxygen delivery to cells and that this will make care easier, safer and cheaper.  Skin is regarded as an early warning sensor, so should give physicians time to prevent lasting damage. Preclinically, transfusion need was detected two hours before kidney failure. Monitoring cellular oxygen in skin should therefore provide early warning of complications and allow doctors to assess the necessity for interventions and follow their effects in real time. It should also facilitate decisions before and during peripheral interventions and be useful to detect alterations of cellular metabolism  and help develop treatments for metabolic dysfunction. Measurements have also been performed in the gut of volunteers and preclinically in other organs. So far, a CE marked sensor is only available for the skin. Eventually, images of cellular oxygen distributions in organs should help assess tissue function for diagnosis, interventions or wound care.