MedChemExpress - Model Cdc7-IN-1 -1402055-25-7
Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].MCE products for research use only. We do not sell to patients.
Cdc7-IN-1
MCE China：Cdc7-IN-1
Brand：MedChemExpress (MCE)
Cat. No.HY-101523
CAS：1402055-25-7
Purity：99.77%
Storage：Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Shipping：Room temperature in continental US; may vary elsewhere.
Description：Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death.
IC50 & Target：IC50: 0.6 nM (Cdc7, at 1 mM ATP)[1] Molecular Weight 409.82
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References：
[1]. Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418. [Content Brief]
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