Comi Polaris - Model HX/GMP -Pharma Peeler Centrifuge

The Pharma Peeler Centrifuge is a horizontal, high-efficiency machine designed to isolate and wash APIs (Active Pharmaceutical Ingredients) in a safe, enclosed environment. With its automatic, reliable, and efficient horizontal configuration, the peeler centrifuge enhances production speed and capacity, making it one of the most modern and commonly used types of centrifuge equipment in the pharmaceutical industry.

APIs are typically created in a reactor or crystallizer. To isolate the API, a horizontal peeler centrifuge with scraper functionality is used, separating the solids from other slurry components through filtration. This filtering peeler centrifuge efficiently collects the solids in the basket while discharging the liquids, incorporating a washing step to increase purity. Mechanically reducing the liquid content reduces the downstream thermal processing requirements such as drying time, thus protecting the quality of the API.

• Active Product Ingredients (APIs)
• Antibiotics
• Pharmaceutical Intermediate Products
• High Potent Active Product Ingredients (HPAPI)
• Vitamins
• Amino, fatty acids
• Steroids

Typical Applications

• Active Product Ingredients (APIs)
• Antibiotics
• Pharmaceutical Intermediate Products
• High Potent Active Product Ingredients (HPAPI)
• Vitamins
• Amino, fatty acids
• Steroids

Highlights

• Ideal for pharmaceutical, Active Pharmaceutical Ingredients (APIs), and potent compound processes
• Maximum purity of discharged products through efficient horizontal peeler configuration
• Small and compact footprint
• cGmp design for CIP and eliminates product stagnation zones
• Laser cake detector (external to process chamber)
• No contact between the operator and the product during operation makes it ideal for pharmaceutical synthesis products
• Through-the-wall installation for clean rooms
• Full access to inspect all areas including rear of basket and shaft seal
• Horizontal basket assures even loading of cake
• Filter medium is easily changed and secured in the basket
• Installation directly on the floor on anti-vibration dampers
• FDA-approved oil lubrication for bearings on all models
• Sizes range from 400mm (15.75 in.) diameter to 1700mm (66.9 in.) diameter 

Discharge

• Knife scraper blade fixed without use of bolts (FOD compliant)
• Suitable for the maximum recovery of solids discharged and the protection of the discharge chute
• Steep solids discharge chute (30° from vertical)
• Heel removal assist with optional blow back to ensure full discharge from the basket
• Options for solids discharge with high containment (use of continuous liner, isolator, etc.)
• Maintenance of shaft and bearings from the rear side of the machine (service area) without contaminating the clean room

Control Options

• Complete PLC controls with touch-screen interface
• Switch between automatic, semi-automatic, and manual operation
• Variable frequency drive (VRD) speed control
• ATEX (Europe) electrical enclosures or NEC (North America)
• Optional instrumentation integrated into the control system including oxygen monitoring, temperature, pressure, liquid feed flow, and N2 purge

Control Options

• Complete PLC controls with touch-screen interface
• Switch between automatic, semi-automatic, and manual operation
• Variable frequency drive (VRD) speed control
• ATEX (Europe) electrical enclosures or NEC (North America)
• Optional instrumentation integrated into the control system including oxygen monitoring, temperature, pressure, liquid feed flow, and N2 purge

Machine Characteristics

• Pressure tight to 400mm H20 (0.6 psig)
• Inert gas purging
• Easily replaceable endless filter cloth, thermo-welded, in polypropylene or PTFE of various weaves and sizes
• Construction materials
• Parts in contact with the product: all stainless steels and special alloys are available, such as AISI 316L, AISI 904L, hastelloy, monel, alloy 59, 254 SMO, nickel, titanium, SAF 2205
• Surface coating option: Halar (ECTFE)
• Elastomers: antistatic and FDA certified, Teflon ETFE, and hard rubber

Technical Services

• Certifications, validation, FDA qualification, and construction documentation
• Field service and technical support available
• Mechanical and electrical parts
• Process control and maintenance manuals
• Mechanical and electrical upgrades