Antec Scientific

µ-PrepCellModel SS -Workhorse Cell - High-performance Electrochemical Cell for Environmental Monitoring

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The new µ-PrepCell SS is the cell of choice for the reduction of disulfide bonds in peptides/proteins including monoclonal antibodies (mAbs). The on-line electrochemical reduction is a real green approach.  Unlike the chemical reduction no expensive enzymes are being used, and also no harsh reagents such as DTT or TECP that often interfere with the LC-MS analysis. Superior characterization has been achieved of proteins in top-down and bottom-up proteomics, including hydrogen-deuterium exchange coupled to MS (HDX-MS).

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  • Efficient reduction of S-S bonds in proteins
  • Long term stability and reproducibility
  • Reagent free, no interfering DTT, TCEP
  • Automated workflow for sequencing and S-S bond assignment