Viva - Model PFP -Propyl Columns (USP L43)

• Excellent for separating peptides or proteins.
• Rugged, spherical particles with 300 Å pore size.
• High proportion of pore/surface area available to large molecules.

Viva columns are based on a wide pore material we designed for optimal large-molecule separations. In developing Viva silica, we found that although many commercial wide-pore silicas meet the standard 300 Å mean pore size, most have very broad distributions about this mean, with a significant portion of their pore volume falling below 150 Å. This means a large portion of the surface area is unavailable to larger molecules. Viva columns have a narrow distribution around the mean pore size, permitting a larger portion of the silica surface to play a role in the separation.

The Restek PFP Propyl is a great choice for the retention and selectivity of charged bases, electronegative compounds, and amine-containing compounds. Unlike a conventional cyano column, the Restek PFP Propyl is much more amenable to LC-MS because it is more reliable and efficient with acidic mobile phases. This versatile column is also compatible with highly aqueous mobile phases and HILIC separations.