Santa Cruz Biotechnology, Inc. - Dextran Sulfate, Sodium Salt MW ~500,000

Dextran sulfate is an anionic polymer of sulfated glucose, capable of accelerating hybridization rates of nucleic acids. The polyanionic character of Dextran sulfate helps to approximate nucleic acid strands, increasing their effective concentration to each other and promoting hybridization. Dextran sulfate also demonstrates a sequestering interaction with proteins, presumably through hydrogen-bonding between the sulfate groups and amine groups of the protein that generates an insoluble complex. The ability of Dextran sulfate to precipitate fibrinogen and low-density lipoproteins from plasma solutions has been used for analysis and for anticoagulant applications. Dextran Sulfate is also known as CCRIS 196, Dexnon, Dextrarine, Dexulate, and DS-M-1.