NanoIntegris HiPco - Model SWCNTs -Single-Wall Carbon Nanotubes

Cancer Gene Therapy

Biochemists at Nanyang Technological University have utilized NanoIntegris’ HiPco Raw powder as an siRNA nanoplex for the gene therapy of pancreatic cancer cells. [1] The 110 nm effective hydrodynamic diameter of the SWNT nanoplex makes them suitable for applications as nanocarriers for intracellular delivery and allowed them to be utilized for gene transfection against the mutant K-Ras gene in PANC-1 pancreatic cells.

Cells treated with the SWNT/PAH/SiRNA nanoplex formulation had the expression level of the targeted mutant K-Ras mRNA suppressed from 100±12.2% down to 66.88±5.14% while possessing low cytotoxicity and high biocompatibility. Such multifunctional and multimodal CNT formulations could be engineered for other advanced healthcare applications, integration with drug moecules, and prove beneficial in theranostics.

Lithium Ion Battery Electrodes

In work performed at the Ulsan National Institute of Science and Technology, in conjunction with other Korean researchers, NanoIntegris’s HiPco SWCNTs were used to generate nanonets showing great promise as a broadly applicable platform technology for high-energy-density/ high performance energy conversion/ storage materials.

HiPco Super Purified powder was combined with PFO and OLO to form an OLO@mSC nanonet of metallic enriched material that enabled significant improvement in the areal mass loading of active materials in the OLO cathode while resulting in the higher areal capacity cells (1.62mAh/cm2 and 213mAh/g cathode). The OLO@mSC cathode showed high discharge capacity, high electronic conductivity ( ~0.10 S/cm), alleviated the rise in cell polarization, showed low internal cell resistances, high capacity retention during cycling (94% after 100 cyles) and facilitated the charge/ discharge reaction during cycling.

LNMO@mSC nanonets were also generated for use with LNMO cathodes. The LNMO@mSC showed a high capacity retention (97% after 200 cyles), had a low charge transfer resistance (RCT=6.6 Ω) with great growth suppression after cycling, indicating promise as electron-conductive shields.

The mSC nanonets were also investigated as a conducting coating layer on a perovskite catalyst – NSC. The NSC@mSC nanonets showed a high ORR onset potential (~-0.12 V) a large diffusion limiting current density (-5.2 mA/cm2), a low Tafel Slope (115 mV per decade), high current density, lower onset potential, and long-term stability after 1000 cyles (91.2%), all indicating that the NSC@mSC may be a promising bifunctional ORR/OER catalyst.

[1] J. Mater. Chem. A, 2017, 5, 12103-12112

• Individual SWNT Diameteri : ~0.8 – 1.2 nm
• Individual SWNT Lengthii : ~400 – 700 nm
• Color : Black, Dark Grey
• Morphology : Dry fibrous powder
• Raman G/D Ratio (532nm)
• Raw: 35
• Purified: 95
• Catalyst Content : <20 wt% (5 Atom%) as Fe
• Carbon Purity :  >80 wt% (95 atom%)
• Carbon as SWCNT (TGA) : >65wt%
• Crystallinity (Raman Analysis) : High
• Raman G/D ratio : Average: ~25
• Highest 95@532nm Excitation