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Twist - High Throughput Antibody
FromTwist Bioscience
The low-throughput, resource-intensive process of antibody variant characterization can be a costly bottleneck in the discovery pipeline. Twist High-Throughput Antibody Production is a gene-to-protein workflow that relieves this bottleneck by producing tens to thousands of diverse antibodies for screening biophysical and pharmacokinetic properties. Twist’s silicon-based DNA synthesis platform can precisely write thousands of genes per run, enabling the rapid and high-throughput production of antibodies for discovery and screening.
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High throughput
- Simultaneous production of thousands of antibody genes
- Flexible scale, from tens to thousands of antibodies
- Rapid turnaround time
Customizable
- Fully customizable antibody sequence
- Use Twist’s vectors, or a vector of your choice
- VHH, scFv-Fc, and IgG isotypes available
One-stop-shop for precision
- We handle DNA synthesis, cloning, expression, and purification
- NGS sequence-perfect genes ensure quality antibodies
- Robust project-to-project expression consistency
Best in class service
- Ph.D. Level scientific support
- Gene scoring tools improve expression potential
- Transparent communication throughout
- Antibodies provided as purified protein or supernatant
- All major isotypes of IgG available: IgG1, IgG2, IgG4, Kappa and Lambda light chain, and VHH-Fc (IgG1 and IgG2)
- Yields range from 15 μg to 2,000 μg
- Antibodies expressed in HEK-293 cells