MedChemExpress LLC (MCE)

MedChemExpressModel TRV055 -25849-90-5

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TRV055, a G-protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV055 is efficacious in stimulating cellular Gq-mediated signaling[1].
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TRV055

MCE China:TRV055

Brand:MedChemExpress (MCE)

Cat. No.HY-P3136

CAS:25849-90-5

Synonyms:TRV120055

Purity:99.75%

Storage:Sealed storage, away from moisture and light, under nitrogen Powder -80°C 2 years -20°C 1 year *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Shipping:Room temperature in continental US; may vary elsewhere.

Description:TRV055, a G-protein-biased agonist, is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV055 is efficacious in stimulating cellular Gq-mediated signaling.

IC50 & Target:AT1 Receptor

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References:

[1]. Laura M Wingler, et al. Angiotensin Analogs with Divergent Bias Stabilize Distinct Receptor Conformations. Cell. 2019 Jan 24;176(3):468-478.e11.  [Content Brief]

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