Zacken - Model ZKN70 -Bacillus Coagulant
Bacillus Coagulant ZKN70 with the facts of high stability, high activity, powerful potency, and super cost-effective, our high-quality strains( Bacillus Coagulant) as feed additives are shown the best sale in the fields of silage feeds, fermented feeds, animal farming, and eco-environment.
Basic Information
- Product name: Bacillus coagulant Powder
- Patented Strain No.: ZKN70
- Cell viable count: NLT 100Billion CFU/g
- Appearance: White To Light Yellow-Colored, Free-Flowing Powder
- Stability: 24months
- Storage: Recommend storage at room temperature.
- Applications: It is commonly used in pharmaceuticals, Dietary Supplements, functional beverages, and animal feeds.
Bacillus coagulant, Gram-positive, belongs to the phylum Hard (or thick) wall bacteria. Condensation. Taxonomically, Bacillus belongs to the genus Bacillus. The cells are rod-shaped, Gram-positive bacteria, terminal spores, and without flagella. It decomposes sugars to produce L-lactic acid, which is a homo-lactic acid fermentation bacteria. The optimum growth temperature is 45~50?, and the optimum pH is 6.6~7.0. The survival rate of Bacillus coagulant in the spore state at a high temperature of 100°C for 10 minutes reaches 96.4%; Under acidic conditions of pH 2.0, the 6-hour survival rate reached 48.2%; the 24-hour survival rate reached 78.3% under the condition of 0.9% bile salt, and the survival rate reached 84.3% under the condition of 0.3% bile salt. It can still survive at a pH of 1.0, but under low pH conditions (pH 4.0), Bacillus coagulant has reduced heat tolerance.
Strain Characteristics
Bacillus coagulant is a facultative anaerobic bacteria that can grow in both aerobic and anaerobic environments. It can adapt to the low-oxygen interaction environment, has a high tolerance to acid and bile, and can carry out lactic acid fermentation to produce The L-lactic acid can lower the pH of the body, inhibit harmful bacteria, and promote the growth and reproduction of beneficial bacteria such as bifidobacteria. The initial micro ecological balance.
Bacillus coagulant bacterial spores germinate in about 4-6 hours in the human body, and 85% of the bacteria can pass through the digestive system smoothly, and finally germinate and multiply in it. Therefore, as an “immigrant” within the interconnection, Bacillus coagulant can only stay in the body for a short time. After a one-time oral administration of Bacillus coagulant bacteria, the internal Bacillus coagulant bacteria will pass defecation after about 4 to 7 days. And disappeared. Therefore, only the continuous absorption of the Bacillus coagulant bacterial agent can make the bacteria fully exert its probiotic effect.
Strain Efficacy
(1) Bacillus coagulant colonizes the cecum, colon, and rectum to produce a large amount of antibacterial coagulin, lactic acid, amino acids, vitamins, and a variety of digestive enzymes.
(2) The survival rate of Bacillus coagulant after being treated with artificial gastric juice (PH 1.4) for 2 hours is 95.29%. It is extremely tolerant to the acidic conditions of artificial gastric juice, and its survival cannot be overcome. Obviously more other microecological preparations can pass smoothly pass through the stomach and enter the intermediate, thus ensuring the normal effect of the medicine.
(3) Facultative anaerobes consume free oxygen to reproduce when they enter the intestinal tract, which is conducive to the growth of anaerobic microorganisms, lactic acid bacteria, and bifidobacteria, thereby regulating the balance of the intestinal microflora and improving the body’s immunity And disease resistance, reduce the occurrence of intestinal diseases.
- After being settled in the body, it can also produce a large number of bacteriostatic substances such as Coagulin and L(+) lactic acid that inhibit harmful bacteria, which has a certain therapeutic effect on inhaled antibiotics.
- In the process of reproduction in the intestinal, amylase and protease are also secreted to promote the digestion and absorption of nutrients; the B vitamins, amino acids, short-chain fatty acids, and other substances it produces can increase the peristaltic speed of the small intestine, thereby improving the intestinal tract The digestive function.
Strain Stability Test
Tolerance report of Bacillus coagulant powder ZKN70 (Annex 1)
Stability report of Bacillus coagulant powder ZKN70 (Annex 2)
- Large feed enterprises, and breeding enterprises: it is directly added to the feed formula;
- Medium and large Animal Pharmaceutical Companies,Animal health companies, or feed additive companies: It is used as one of the key functional ingredients;
- Compounding into microecological preparation products, the first choice of green additives for export-oriented breeding enterprises;
- It can be widely used as feed additives for livestock, aquatic products, ruminants, silage starter, and pet health care.