Reaction Biology Corp.

Bromodomain Assay Service

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Bromodomain screening and profiling of reader domains such as Tudor and chromodomains are performed at Reaction Biology via Thermo Shift and AlphaScreen assays. More than 85 bromodomain assays and 30 other epigenetic reader domain assays are available for screening, lead optimization, or selectivity profiling for reader domain inhibitors.

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Several potent bromodomain inhibitors have recently been identified, increasing the appreciation of the reader domain family’s functional importance and therapeutic potential. At Reaction Biology, we are continuously developing new reader domain assays.

  • Extensive coverage of the bromodomain family.
  • All bromodomain proteins and other reader domain proteins are produced at our facility and are available for purchase.
  • The BromoMELTTM assay kit is available for in-house bromodomain inhibitor screening.