Inotiv
Developmental and Reproductive Toxicology Service
FromInotiv
We offer a broad scope and wide range of DART services: Fertility (male and/or female); Embryo-fetal development/prenatal developmental toxicity study; Prenatal and postnatal development, including maternal function; Combined 28-day/reproduction screening; One- and two-generation reproduction study; EOGRTS.
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Scope and range of services:
- Studies
- OECD 426: Developmental neurotoxicity study
- EPA OPPTS 870.6300: Developmental neurotoxicity study
- Evaluations
- Clinical observations and bodyweight
- Neuropathology (immersion or perfusion fixation)
- Sexual maturation
- Other developmental landmarks
- Behavioral ontogeny
- Motor activity
- Motor and sensory function (auditory startle)
- Learning and memory
Scope and range of services:
- Customized study designs
- Species selection and age for intended patient populations
- Consideration of timing of dosing, exposure, monitoring, pharmacological/toxicological differences
- Evaluations
- Routine and target organ toxicological endpoints
- Nervous system
- Reproductive systems
- Skeletal system (growth)
- Neurobehavioral
