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MARIA Analysis Services
The Multiplex Array for Indoor Allergens (MARIA®) combines Indoor Biotechnologies proprietary panels of monoclonal antibodies with the Luminex xMAP® multiplexing technology. MARIA® technology uses polystyrene microspheres that are internally dyed with distinct fluorophores to create as many as 100 distinctly coded bead sets. Capture antibodies are covalently coupled to different bead sets and then used to develop quantitative immunoassays using biotinylated detector antibodies and a reporting fluorophore.
Up to 13 common allergens of dust mite (Der p 1, Der f 1, Der p 2 and Der p 23), cat (Fel d 1), dog (Can f 1), mouse (Mus m 1), rat (Rat n 1), cockroach (Bla g 2), molds Alternaria (Alt a 1) and Aspergillus (Asp f 1) and the pollen allergens of birch (Bet v 1) and timothy grass (Phl p 5) can currently be measured simultaneously using this technology. The detection panel is continuously being enlarged to include other allergens, such as food allergens.
Check our Technical Information on MARIA® for more details on the bead based assay and for a comparison with the tradional ELISA method. Whatever the choice, Indoor Biotechnologies can provide assistance and training in setting up laboratories for ELISA or MARIA®. Almost all the commercial allergen testing laboratories in the U.S. (and elsewhere) use our assays. Most of these labs have been trained by Indoor Biotechnologies professional staff on our annual training course or have received customized training through our company.
Become Part of the Solution
Indoor Biotechnologies provides comprehensive allergen testing services worldwide. We partner with companies from the indoor air quality, occupational health and industrial hygiene industry to expand the provision of allergen exposure assessments. This helps companies become part of the solution and to address environmental exposures in the home and the workplace that have known health effects.
Indoor Biotechnologies can help:
- We work with companies to establish an allergen analysis laboratory, or to incorporate allergen testing in existing laboratories. We also provide specialized training in sample collection, immunoassays, data analysis and interpretation of exposure levels.
- We partner with companies who do not have laboratory facilities and provide them and their clients with professional allergen analysis services. Our ISO 17025 compliant Environmental Testing Laboratory provides INDOOR® Allergen Analysis Services for clients by MARIA® and ELISA. We have established a network of companies who regularly send samples to Indoor Biotechnologies for allergen analysis and who receive quantity discounts and other benefits from the partnership.