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MtoZ Biolabs - Model exosome-proteomics -Exosome Proteomics Service
Exosomes are one of the common extracellular vesicles (EVs) with diameters ranging from 30 to 150 nm. They primarily originate from the invagination of lysosomal particles into multivesicular bodies, which are released into the extracellular matrix, such as tissues and various biological fluids including serum/plasma, cerebrospinal fluid, and urine (in vivo), after the outer membrane of the multivesicular body fuses with the cell membrane. Additionally, exosomes can also exist in vitro under certain conditions in culture media. EVs play an important role in various physiological processes, and compared to general EVs, the function of exosomes in the field of clinical biomarkers is still unclear. With the development of exosome separation technologies, interest in this field is growing, and it is anticipated that more detailed studies on the function and applications of exosomes in disease pathologies will emerge.
Exosomes primarily contain a complex mixture of proteins, lipids, RNA, etc. The content and function of exosomes from different biological fluids vary, and compared to other contents, proteins play a crucial role in biological functions. Therefore, proteomic analysis of exosomes from different biological samples is significant for the discovery of biomarkers and clinical diagnosis.
MtoZ Biolabs provides professional and comprehensive exosomal proteomics analysis services, capable of identifying and quantifying proteins in exosomes. By integrating bioinformatics techniques for the analysis of proteomic data, the detection of biomarkers can be achieved.
Sun, Y. et al. Anal. Chim. Acta. 2017.
1. One-stop Exosome Proteomics Analysis
We can complete the entire process including exosome separation to protein identification and quantification. It is possible to separate exosomes from various types of samples, including plasma/serum, cerebrospinal fluid, saliva, snot, urine, bile, and cell culture media.
2. Advanced Facilities and Optimized Operation Procedures
MtoZ Biolabs uses the currently highest resolution and sensitivity mass spectrometer, the newly introduced Obitrap Fusion Lumos by Thermo company, combined with nanoLC chromatography for exosomal proteomics analysis. MtoZ Biolabs has extensive experience in the field of exosome proteomics analysis and can provide customized services.
3. Biomarker Detection through Bioinformatics Analysis
Our professional bioinformatics analysts are proficient in using various bioinformatics analysis tools, providing in-depth analysis and data mining.
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com