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MtoZ Biolabs - Model purity-analysis-of-peptides-or-proteins -Protein Purity and Homogeneity Characterization Service
Protein purity and uniformity are crucial for protein crystallization as well as structural and functional studies. Impure samples can lead to inaccurate results in experiments. Additionally, protein purity and uniformity are two very important characteristics for further protein research and biopharmaceutical applications. The purity of protein samples limits the application of protein products.
Common contaminants in protein products include culture media, reagents used in extraction and purification,etc. Beyond impurities, protein non-uniformity may be due to different intracellular reactions and post-translational modifications. It is important to analyze the purity and uniformity of proteins before further processing.
Figure 1. Characterization of Protein Purity and Uniformity Marked by pI
MtoZ Biolabs offers a range of services for characterizing protein purity and uniformity, aiming at detecting contaminants, protein variants, isomers, S-S chain mismatches, truncated proteins, degraded proteins, protein modifications, protein aggregates, and protein precursors.
1. Purity and Integrity Analysis Methods
SDS-PAGE, capillary electrophoresis, zinc reverse staining, aldehyde-free silver staining and MALDI-TOF MS.
2. Uniformity Analysis
Dynamic light scattering, UV-visible spectroscopy, size exclusion chromatography and static light scattering.
We can handle samples such as antibodies, antigens, enzymes, growth factors, DNA-binding proteins, blood proteins, and membrane proteins. Common samples include:
1. Proteins From Natural Sources
2. Recombinant Fusion and Tagged Proteins
3. Antibodies of Different Subtypes
4. Membrane Proteins
1. Advanced Technical Platform
We are equipped with various technical platforms to accurately determine the purity and uniformity of proteins.
2. Accuracy and Reproducibility
We provide accurate and detailed results on sample purity and uniformity to save time wasted on poor samples.
3. Wide Application Scope
Purified and homogeneous proteins can be used for research and medical applications, such as the development and quality control of therapeutic proteins.
MtoZ Biolabs offers various methods to economically and efficiently characterize samples and provides reliable and detailed data reports. For specific service, please contact our technical staff.
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com