Ab Studio Inc.
Quick In-Silico Antibody Affinity Maturation Services
FromAb Studio Inc.
Quick in-silico antibody affinity maturation based on antigen/antibody interface analysis, application of Ab Studio’s unique biochemical filter and on-bench verification.
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- Build up the model for antigen/antibody complex Quick in-silico antibody affinity maturation based on antigen/antibody interface analysis, application of Ab Studio’s unique biochemical filter and on-bench verification. The antigen/antibody model is built using AlphaFold, the most advanced artificial intellegence software for protein modeling.
- Analysis of interface residues Ab Studio Inc. The established antigen/antibody complex allows for the detection of interface residues. With expertise in antibody design, appropriate residues will be chosen to undergo affinity maturation
- Affinity maturation calculations Biophysical calculations will dictate the first level of the affinity maturation design. Then, Ab Studio’s unique biochemical filter will be applied to complete the design.
- On-bench verification All designs will be verified through cell binding, ELISA, or biolayer interferometry (BLI) methods.
