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GenscriptSite-Directed Mutagenesis Services

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Site-directed mutagenesis facilitates life science research by creating specific DNA mutations (including point mutations, deletion mutations, and insertion mutations) to enable studies of gene regulatory elements, DNA-protein interactions, protein structure/function, enzyme active sites, and novel proteins.

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GenScript`s site-directed mutagenesis services provide a fast, cost-saving, way to get 100% accurate mutant DNA clones, without having to spend your time and money on mutagenesis kits to do PCR mutagenesis, cloning, and sequencing in your own lab. Powered by our industry-leading gene synthesis technology and high-performance GS polymerase, GenScript can make any gene template and any number of mutations, starting at just $99/mutant and 5-day turnaround time.

  • Unparalleled Accuracy:GenScript`s high performance GS polymerase ensures accuracy of mutants, avoiding creation of unwanted mutations.
  • Unlimited Sites:Using our sophisticated gene synthesis and mutagenesis techniques, GenScript can introduce mutations at any site.
  • Mutations on Large DNA Constructs:Our technology is optimized to introduce point mutations, insertion mutations, and deletion mutations on constructs as large as 12 kb (including target gene and its vector).
  • One-stop solutions:We offer comprehensive upstream and downstream services, including template DNA sequencing, de novo gene synthesis, Express Cloning into free expression vectors, customized vector construction, and protein expression and purification.
  • Most Competitive Pricesstarting at $99/mutant.