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MtoZ Biolabs - Model swath -SWATH
Sequential Window Acquisition of all Theoretical fragment ions (SWATH) is a brand new mass spectrometry technology co-developed by Dr. Ruedi Aebersold research group (ETH Zürich) and AB SCIEX. SWATH data is an independent acquisition (DIA) technique. Unlike data dependent acquisition technique, which only selects certain MS spectrum for MS/MS detection, SWATH analyzes all MS and MS/MS spectra, allowing detection of virtually all detectable proteins in a sample. In SWATH technology, MS spectra are divided into several narrow windows and peptides in each window are sequentially analyzed equally, followed by MS/MS analysis. SWATH technique combines the high-throughput quality of shotgun proteomics with high accuracy comparable to . To better meet our clients’ needs, MtoZ Biolabs offers a comprehensive SWATH service, including optimized sample preparation, high-quality SWATH mass spectrometry analysis and professional bioinformatics analysis.MRM
AB SCIEX Triple-TOF 5600-plus
1. Quantitatively Analyze Nearly All Detectable Molecules, Including Low Abundance Proteins and Peptides
2. High Accuracy, Comparable to MRM Level
3. High-Throughput, Identify and Quantitate More than 2000 Proteins at Once
4. Complete Digital Archive of Sample in the First Analysis
5. Pre-Experiment Method Development is Unnecessary
1. SWATH Data Quality Assessment
2. Multivariate PCA Analysis
3. Protein Statistical Analysis: Venn Diagram, Volcano Plot
4. Functional Annotation: GO Annotation, KEGG Annotation, COG Annotation
5. Clustering Analysis: Hierarchical Clustering, K-Means Clustering
6. Network Analysis: STRING Analysis
1. Experiment Procedures
2. Parameters of Liquid Chromatography and Mass Spectrometer
3. MS Raw Data Files
4. Peptide Identifications and Intensities
5. Protein Identifications and Intensities
6. Bioinformatics Analysis
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com