Intrinsik Inc.

Toxicological Sciences Services

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Intrinsik toxicologists, including eight Board Certified Toxicologists (DABTs and ERTs), bring significant experience spanning the full spectrum of toxicological sciences.  Our toxicological and risk assessment experience and expertise allows us to address almost many problems our clients may have related to chemical exposure and human health. Intrinsik has extensive experience working with regulatory agencies on emerging toxicological issues to effectively guide our clients through complex and often confusing technical guideline requirements. Intrinsik scientists are active professionals contributing to evolving issues in the area of toxicological sciences.

As a result of our expertise, we can handle complex and emerging environmental toxicology issues with state-of-the-science approaches and provide reliable scientific interpretations of the findings. Intrinsik toxicologists are skilled in designing, generating and analyzing toxicological data to accurately characterize the health effects from chemicals in the environment. We are also effective communicators of complex scientific issues to ensure the questions and concerns of stakeholders can be addressed.

Areas where we provide toxicological services to our clients include:

  • Development of Toxicity Reference Values (TRVs) and Environmental Criteria
  • Application and interpretation of Epidemiology Data
  • Toxicokinetic (TK) Research
  • Mode of Action Research
  • Applied Toxicology Research
  • Dose-Response Modelling (Benchmark Dose, Cancer Slope)
  • Application of Quantitative-Structure-Activity-Relationship (QSAR)
  • Physiological-Based Pharmacokinetic (PBPK) modeling
  • Bioaccessibility/Bioavailability Assessment
  • Endocrine Disruptor Screening Program (EDSP)
  • Emerging areas such as Risk21
  • Managing Guideline Studies with TK Insight
  • Use of Biomonitoring data to ground-truth toxicological criteria and exposure

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