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Byos - Desktop Software

Byos - Desktop Software

Launch mass spec analytical workflows with one click! Seamlessly progress from raw file to report on complex biotherapeutics. In minutes. Byos® is a vendor-neutral application that significantly improves laboratory efficiency, reproducibility, and reporting.

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process automation

capillary electrophoresis mass spectrometry

Byonic™ is our full MS/MS search engine providing unequalled sensitivity for comprehensive peptide and protein identification. As a node in Byos®, Byonic™ results are incorporated automatically along with the raw mass spec data and any HPLC data.

Intact, Sub-unit, and Native Analysis

Ligand binding
Protein-protein interaction
Protein and subunit ID
Glyco-profiling
ADC and DAR analysis
Charge Variants by iCIEF-MS and CE-MS

Peptide-level Analysis

Hotspot analysis
Peptide mapping
PTM analysis
HCP analysis
Sequence variant analysis
Epitope mapping

Chromatogram Analysis

MAM workflows
CE-UV data; SEC-UV, LC-UV & other chromatographic workflows
Import of 2D trace data

De novo Sequencing

Hands-free, automated sequencing of purified mAbs

Oligos

Oligonucleotide workflows
Impurities and clips
Sequence confirmation for known oligos

Released Glycan

O-linked & N-linked Released glycans – +ve & -ve modes
Automated processing of fluorescently tagged glycans
pre-prepared libraries

Higher Order Structure

HDX and FPOP workflows
Epitope mapping, paratope mapping, other higher order structure work
Representation in .pdb format

HRIM

Workflows for Mobie
Released Glycan, Intact and Peptide mapping workflows

iCIEF

Intabio iCIEF workflows
Representation on a pI axis with deconvolution

Byos - Desktop Software

Byonic

Workflows