Biotechnology companies are amongst the most innovative and fast paced in research and development. Scientists endeavour to discover the latest drug molecule or learn how to grow more crops for fewer resources. Research in these areas can create vast quantities of disparate data and without the right tools scientists can struggle to interpret their data. Dotmatics data management and analysis solutions have the power and flexibility to meet the needs of the ever changing and diverse biotech industry. Our solutions allow scientists to capture and analyze research data, unrivalled querying and reporting functionality, and sophisticated visualization to overcome the data challenges of biotechnology companies of all sizes and disciplines.

Find out how Dotmatics can help with the challenges of these areas of biotechnology:

Analytical chemistry and Bioanalysis

Capturing and storing the quantitative results of analysis on small and macromolecules is essential for information flow through the discovery process.

Studies Notebook, Dotmatics electronic laboratory notebook for chemistry and biology provides a highly configurable form based solution for entry of experimental data. Microsoft Office documents can be stored and text indexed for more ad-hoc results.

Biotherapeutics

The number of biotherapeutic drugs in the market is increasing as more companies are looking to macromolecules for the next blockbuster drug molecule. This has created new challenges in biotechnology for data registration and management of biological entities.

Bioregister from Dotmatics for registering and managing biological entities through the drug discovery process offers a solution to tracking unique biological entities, managing data associated with their production including, expression, purification and characterisation and can track sequence information.

Screening

Searching for active drug molecules is expensive and time consuming and using modern screening techniques can produce millions of chemical, genetic or pharmacological results. Managing the data associated with these experiments is fundamental to the success of a biotechnology company of any size.

Using Dotmatics Studies solution for assay management scientists can analyze the raw instrument data quickly and effectively and store this directly in the database. This data can then be fully queried and reported, including plots using Dotmatics Browser solution. This makes it simple to query and report biological screening results and chemical data in one place.

Vortex from Dotmatics is a powerful visualization tool for screening data that can process hits from your screening campaigns in an automated approach. Plate data can be visualized out-of-the-box and used to analyse activity and data quality. Chemical series can also be analyzed to give insights for future screening projects.

Small Molecule Drug Discovery

The small molecule discovery industry is very competitive with many companies competing to discover drugs to act on the same target. It is crucial that biotechnology groups focusing on chemical molecules effectively manage their chemistry and biology data. Chemical libraries can reach in excess of million compounds along with associated biological screening results with each molecule. Storing data in Excel and SD files soon becomes unmanageable.

Browser from Dotmatics provides a project centric query and reporting solution that brings together all chemistry and biological data from a single or multiple disparate databases. It can also bring together data from third party database solutions to create a union of all discovery data.

Register from Dotmatics allows chemistry groups to create a corporate registration database. Scientists can perform single compound registration or a collection of molecules through an SD files registration. Register easily manages salt and batch information as well as any other associated Meta data.

Studies from Dotmatics allow small molecule focused biology groups to analyze plate or non plate based assays. Many of the typical analysis types are included out-of-the-box including IC50, EC50 and %inh. Scientists can also configure their own defined equations for analysis.

Vortex from Dotmatics allows small molecule discovery groups to visualize chemistry and biology data to perform structure activity relationship analysis. An array of plots and tools allow scientists to find trends, activity and outliers in data with chemical intelligence.

Dotmatics provides the following solutions for Biotechnology:

Data organisation, querying and reporting

Browser is a flexible and powerful web-based query and reporting solution. Built in collaboration with scientists, Browser can be completely tailored to the needs of any industry. The solution integrates all disparate databases into a central place to share data from any geographical location with colleagues or collaborators.

Experimental data capture

Studies Notebook is an Electronic Laboratory Notebook (ELN) that covers all scientific disciplines in a single interface including full handling of chemistry and biology experimental data. It is the only truly web-based ELN that allows every entered field to be fully searchable.

Biological data analysis and storage

Studies is the standard in screening data management, with a completely web-based interface and unrivalled flexibility which allows the creation, capture, analysis and storage of chemical, biological and ad-hoc research data.

Analyze and visualize your datasets

Vortex is a data visualization solution for driving decision making for scientists in the biotechnology industry. Vortex includes the plots and tools required to explore trends in your data. Full chemical intelligence is included for chemistry users.

Chemical structure editing

Elemental is a comprehensive structure editor that is central to any chemical entry or searching within the Dotmatics suite of solutions. Elemental includes the ability to create stereochemistry, support reactions and high resolution imagines for presentations.

Simple flat files database upload

Nucleus is a simple, yet powerful database importing solution for flat data files. Scientists can quickly import data from legacy data, in-house results or data from external partners directly into the database.

Registry and storage of chemistry

Register is a fully integrated, web-based compound, sample and inventory data management solution. Register enables a drug discovery organisation to development their corporate registration database.

Registration and management of biological entities

Bioregister is a web-based platform for registering biological entities, managing data associated with protein production and tracking sequence and batch information through the discovery process.

Indexing and searching of chemical molecules

Pinpoint is a powerful oracle chemical cartridge for querying and integrating chemical databases. Pinpoint represents world class indexing and search performance.

Share and manage documents

Gateway is a document management solution that serves as a central place for all projects teams throughout the organisation to share information. Teams can also securely share information with external partners making it a useful solution for contract research organisations.

Incorporate chemical structures in your Microsoft Office Documents

Dotmatics for Office (D4O) allows chemistry to become live within your Microsoft office documents. Draw chemical structures, calculate physical chemistry properties and perform substructure searches, all within Microsoft office.

Dotmatics - Electronic Lab Notebook