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Thermo Scientific BioPharmaVersion 5.0 -Finder Software

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Complete biotherapeutic characterization: Complete characterization includes intact mass analysis, peptide mapping, oligonucleotide analysis, top- and bottom-down analysis or multi-attribute method (MAM) workflows. Access workflows that facilitate comprehensive interpretation and data visualization, allowing you to confidently characterize your biologics with speed and ease. From novel deconvolution algorithms generating complete results to easy-to-understand data visualization tools, Thermo Scientific BioPharma Finder software helps you choose the right path for confident characterization.

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Simplify and streamline your workflow analysis using a single software platform

  • Efficiently perform intact analysis, top- and middle-down analysis, HDX and peptide mapping analyses through extensive and efficient workflows.
  • From batch processing to in-depth data analyses, workflows guide experts and non-experts to set up, interpret and visualize results, accessing the knowledge contained within any analyzed samples.

Utilize the accuracy of your high-resolution data for confident intact mass analyses

  • For absolute confidence in your deconvoluted molecular weights in both acidic and native conditions, superior algorithms make the most of high-quality Thermo Scientific Orbitrap mass analyzer data.
  • Use all your data, not just a slice, for greater accuracy in deconvolution and relative quantitation of isoforms and drug-to-antibody ratios with the Slide Window algorithm.

Know more than ever about your peptide sequence

  • Rapidly process single or multiple data files to identify sequence coverage, expected and unexpected PTMs, disulfide bonds and sequence variants.
  • Full MS, MS2 experimental vs. predicted spectra and fragment coverage maps increase confidence in your peptide sequence, with data visualization tools facilitating deeper insights into your peptide maps.

Completely characterize process and product quality attributes for high throughput QC monitoring

  • Confidently discover, identify, quantify and monitor product quality attributes with easy-to-understand data visualization within a single software platform.
  • For those requiring compliance tools for GxP compliant monitoring, seamlessly transfer all information from the BioPharma Finder software into the Thermo Scientific Chromeleon 7.2 Chromatography Data System (CDS) for targeted quantitation and new peak detection of peptides and intact proteins.

The complexity of lifesaving therapies under investigation in the biopharmaceutical industry brings significant challenges from research and discovery, through to development and lot-release and quality control. Some of the toughest tasks for analysts and QC chemists are adequately characterizing these large molecules and subsequently monitoring their quality attributes throughout the manufacturing process.

Find out what it takes to go smoothly from sample to knowledge.