Version Blaze -Advanced Ligand-based Virtual Screening Software

Make efficient use of your time by routinely running a virtual screen in parallel to wet screening. A virtual screen of 10 million structures just takes a few hours.

Blaze has been delivering lead-like hits to our customers for almost 20 years. They have achieved hit rates as high as 30%, but what they really value is the diversity of hits returned from every Blaze screen.

• Carry out biologically relevant virtual screens of large chemical databases
• Use the electrostatic character and shape of known ligands to rapidly search large chemical collections for molecules with similar properties
• Increase the diversity of your project’s leads and back-ups
• Jump into new areas of chemical space
• Find novel lead-like hits from known actives
• Replace peptides with non-peptides or steroids with non-steroids
• Achieve substantial improvements in the properties of your hits
• Search algorithm increases search speed fourfold

• Install Blaze on your CPU or GPU Linux clusters
• Deploy our Amazon-ready version of Blaze
• Access Blaze Cloud on Cresset hardware via a secure web portal
• All commands are accessible through a web-based GUI, or thorugh a RESTful web service API
• Blaze virtual screens can also be accessed through workflow tools such as KNIME or Pipeline Pilot
• Engage Cresset Discovery to carry out a virtual screening project