AFFINImeter by Software 4 Science Developments software
AFFINImeter - Advanced ITC Plan with Model Builder for Complex Interacting Systems
The Advanced ITC Plan from AFFINImeter is specifically crafted for both novice and seasoned ITC users dealing with complex interacting systems that deviate from standard binding models. This comprehensive plan includes the fundamentals of the Basic Plan augmented with advanced analytical tools, such as the 'model builder' which enables users to design custom binding models with ease. Furthermore, the plan supports global fitting across multiple isotherms, enhancing its applicability for diverse ITC experiments. It is particularly beneficial for situations involving interactions like those of two competing ligands. The plan is expandable for teams, offering multi-user licenses ideal for research groups with a primary administrator managing accounts. Offered as a cloud-based software, it facilitates seamless access and data analysis from any internet-connected device, although a local installation option exists for restrictive data policies. AFFINImeter supports various instruments including Microcal and TA Nano-ITC models.AFFINImeter - Basic ITC Plan
The Basic ITC Plan is tailored for both novice and seasoned users engaged in isothermal titration calorimetry (ITC), particularly those working with systems adhering to conventional stoichiometric binding models. The plan offers a suite of predefined models, simplifying the analysis process more efficiently than traditional software solutions. A notable feature is KinITC, enabling the extraction of kinetic parameters such as the rate constants (kon and koff) and thermodynamic properties (KA and ΔH) from a single titration experiment, applicable to 1:1 and 1:n interactions. This plan is compatible with various popular instruments including Microcal PEAQ-ITC, Microcal VP-ITC, and TA instruments. While primarily available as a cloud service for seamless data access from any internet-connected device, local software installations are available on request, accommodating institutions with specific data policies.