Akadeum Life Sciences products

Using BACS™ microbubble technology, the Human T Cell Activation & Expansion Kit was designed to isolate highly pure populations of T cells and activate them for use in cell therapy workflows. T cells are isolated, activated, and expanded using Akadeum’s Activation & Expansion Microbubbles in combination with an antibody cocktail that targets CD3 and CD28. This immensely scalable process yields the large numbers of highly activated and transducable cells needed to manufacture potent cell therapies. In addition, the gentleness of flotation-based culture results in fewer exhausted cells than legacy activation methods. Scalable to fit your cell therapy workflow needs. Closed-system in-bag workflows available. Reduced cellular exhaustion during T cell activation and expansion. Increased numbers of highly activated effector T cell populations. Industry-standard T cell expansion kinetics.

Isolate truly untouched Human Leukopak Peripheral Blood Mononuclear Cells (PBMCs) directly from leukapheresis material without the need for lysis or density gradient centrifugation. The Microbubble Leukopak Human PBMC Isolation Kit was developed with BACS™ Microbubbles to isolate untouched Leukopak PBMCs from leukapheresis material. Non-PBMCs are targeted and removed with antibodies recognizing CD66b, CD123, CD235ab via negative selection. Isolated Leukopak PBMCs are suitable for flow cytometry, molecular assays, activation and expansion, cell culture, and other functional studies. The Microbubble Leukopak Human PBMC Isolation Kit has the capacity to isolate PBMCs from an average half-leukopak (12.5 x 10⁹ total cells, red blood cells and white blood cells combined). 

With quality standards built into the design and manufacturing process at ever step, use our Microbubble Leukopak Human T Cell Isolation Kit – GMP Grade to isolate truly untouched T cells directly from leukapheresis material without the need for lysis or density gradient centrifugation. The Microbubble Leukopak Human T Cell Isolation Kit – GMP Grade was developed with BACS™ Microbubbles to negatively select untouched T cells from leukpak material. Non-T cells are targeted and removed with antibodies recognizing CD14, CD16, CD19, CD20, CD36, CD56, CD123, CD235ab via negative selection. Isolated T cells are suitable for a wide variety of downstream assays, including cell culture, flow cytometry, scRNA-Seq, or other functional studies. The Microbubble Leukopak Human T Cell Isolation Kit – GMP has the capacity to isolate T cells from an average half-leukopak (12.5 x 109 total cells).