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In Inductively-Coupled Plasma – Mass Spectrometry (ICP-MS), an inductively coupled plasma (argon gas ionised by an intense electromagnetic field) is used to create ions which are then separated on a charge-to-mass basis and quantified by a mass spectrometer, to as low as ppq detection limits. The intensity of the ion is proportional to the concentration of the sample. Compared to ICP-OES, it gives much lower detection limits. This course engenders a holistic approach to ICP-MS from the initial choice of analytical set-up through to designing a robust methodology including sample preparation and sample introduction and finishing with calibration. Different applications of ICP-MS will be explored throughout the course. Classroom exercises will explore the knowledge learned through the course. Who is this course for? This is an intermediate level course going into reasonable depth on how an ICP-MS instrument works, using, maintaining and troubleshooting it.
This course looks at method validation from start (initial planning) to finish (on-going tracking of performance statistics). Starting with describing the end goal of the analysis and feeding these objectives into research and planning. You will consider the six main areas of a method: sampling, sample transportation & storage, sample preparation, sample analysis, data analysis and reporting. Who is this course for? This course is aimed at delegates with good knowledge of a base technique e.g. GC (or GC-MS) or LC (or LC-MS) and would like to learn more about method validation. Delegates requiring refresher training will also benefit. Whether you are a PhD student developing your research method or you work in a contract laboratory, you will benefit from attending this course!
The 5-day Comprehensive GC-MS introduces the fundamental theory of single quadrupole GC-MS along with the operation, maintenance and troubleshooting of the Agilent single quadrupole Mass Spectrometer using MassHunter software. This course includes an introduction to quadrupole mass spectrometry, method development and troubleshooting; hardware configuration; MS tuning; data acquisition in scan and selected ion monitoring (SIM) modes; qualitative & quantitative data analysis; reports; sequencing; Retention Time Locking (RTL); an introduction to deconvolution; and method maintenance. Who is this course for? This course is primarily for analysts and technicians responsible for the operation, maintenance and troubleshooting of Agilent single quadrupole GC-MS instruments using MassHunter software.
The Complete LC & LC-MS course is built from the Practical Essentials of LC & LC-MS and the LC & LC-MS Clinic courses to provide a complete training solution enabling you to understand your Liquid Chromatograph or LC-MS instrument, application method development, troubleshooting & maintenance. Who is this course for? The Complete LC & LC-MS course is for those who have basic knowledge of liquid chromatography and would like to greatly enhance it, learning the practical theory about all available LC & LC-MS techniques. For complete beginners it is advisable to first attend the Absolute Basics of LC & LC-MS
This course provides an introduction for beginners to Size Exclusion Chromatography. What is size exclusion chromatography? Why do we use size exclusion chromatography? How could it help solve problems and what answers could it give? When do we use size exclusion chromatography? What types of analytes and samples can you use SEC for? How does size exclusion chromatography work? and what instrumentation is available? Where do we use size exclusion chromatography? Which applications to answer what questions? Who is this course for? If you have no or very little knowledge of Size Exclusion Chromatography, are an analyst, technician, engineer or work in sales but have some experience with chromatography, then this is the course for you. This course is ideal either as stand-alone or prior to attending more bespoke SEC application development training.
This course engenders a holistic approach to ICP-OES from the initial choice of analytical set-up through to designing a robust methodology including sample preparation and sample introduction and finishing with calibration. Ten real-world case studies cover elemental analysis in pharmaceuticals, drinking water, soils, motor oil, occupational hygiene, forensics, metal speciation, isotope ratios and food / drink authentication. Who is this course for? Primarily beginners but intermediate users requiring refresher training will also benefit.
A perfect introduction for absolute beginners to mass spectrometry imaging (MSI). The course covers: What is mass spectrometry imaging? Why do we use mass spectrometry imaging? How could it help solve problems and what answers could it give? When do we use mass spectrometry imaging? What types of analytes and samples can you use MSI for? How does mass spectrometry imaging work? What instrumentation is available? Where do we use mass spectrometry imaging? Which applications to answer what questions? Who is this for? Beginner Analysts or Technicians looking for a refresher Lab Managers and Line Managers – those responsible for the instruments or the analysts using them. Data Analysts and Report Writers – technical specialists who aren’t using the instruments but are using data from them. Service Engineers and Consultant Engineers – those who look after or recommend the use of these instruments but don’t have the chemistry background or chemistry viewpoint.
This practical software course on the powerful Automated Mass Spectral Deconvolution and Identification System software mixes 50% presentations with 50% practical exercises using the software to get a good grasp of its capabilities in performing deconvolution to process your GC-MS data. If you have complex samples with little chromatographic resolution or you need to check you have no co-elutions in your chromatogram, learn about using your analytical resolution with mass spectral deconvolution to unravel your mixed mass spectra for confirmation or identification of your co-eluting peaks. Who is this course for? If you need practical guidance to help you understand how to use AMDIS software to make the most of your analytical resolution to perform deconvolution and obtained cleaned-up mass spectra, then this is a course for you. This course requires fundamental knowledge of GC-MS and some background in understanding mass spectra.
This course provides the theory of gas chromatography (GC) and mass spectrometry (MS) essential to any participant, along with hands-on practical elements in the laboratory to practice and re-enforce the theoretical knowledge. These courses are 50% theory and 50% practical in a lab environment. This course combines the five individual hands-on days covering GC Theory and Methods, GC Maintenance, GC-MS Theory and Methods, GC-MS Maintenance and GC and GC-MS Troubleshooting. Who is this course for? This course is suitable for all levels of knowledge; however for complete beginners it is advisable to attend the Absolute Basics of GC & GC-MS first to get a good basic overview of gas chromatography and GC-MS.
This course provides an overview of the history, development and current use of chemometrics in fields such as clinical, environmental, flavour and fragrance & biotechnology applications and its use in method development. The course opens with a “walk-though” summary of the workflows in a chemometrics study, as an example, and goes on to outline the considerations when designing a chemometrics experiment or study including sampling and quality control, metadata and sample preparation techniques. The course will provide an overview of different Mass Spectrometry-based instrumentation and other techniques (such as NMR and Infrared) that produce data used for chemometric analysis. Who is this course for? If you have no or very little knowledge of Chemometrics and would like to improve your knowledge in this area, then this is the course for you.
This course covers all the practical theory about Fourier Transform InfraRed spectroscopy. It will review the EM spectrum focussing on the IR region. It will detail the characteristic absorption spectra of various compounds such as alkanes, alkynes, alcohols, esters, ethers, and will provide examples in the form of exercises for IR interpretation. The course will review the different components of FTIR such as IR sources, detectors, beam splitter and Attenuated Total Reflectance (ATR). It will guide the delegate with sample-specific factors affecting spectral quality and mixtures. The hands-on practicals will include the analysis of pharmaceutical and food samples by FTIR and then will analyse the data. Who is this course for? This course is suitable for all levels of knowledge.
This course provides the theory of HPLC and LC-MS essential to any participant, along with the hands-on practical element in the laboratory to practice and re-enforce the theoretical knowledge. These courses are 50% theory and 50% practical in a lab environment. After an introduction to liquid chromatography, this course addresses solvents & buffers (the mobile phase), pumps, isocratic and gradient elution, sample introduction, analytical columns, HPLC detectors, mass spectrometry including tuning, ionisation, mass analysers, ion detector and data analysis. This course combines the five individual hands-on days covering HPLC Theory and Methods, HPLC Maintenance, LC-MS Theory and Methods, LC-MS Maintenance and HPLC & LC-MS Troubleshooting. Who is this course for? This course is suitable for all levels of knowledge; however for complete beginners it is advisable to attend the Absolute Basics of HPLC & LC-MS first to get a good basic overview of liquid chromatography and LC-MS.
This is a perfect introduction for absolute beginners to liquid chromatography and LC-MS. The course will cover the what, how, why, where and when of LC & LC-MS. What is liquid chromatography, mass spectrometry, a HPLC or LC-MS? How does liquid chromatography work? and what instrumentation is available? Why do we use liquid chromatography? How could it help solve problems and what answers could it give? Where do we use liquid chromatography? Which applications to answer what questions? When do we use liquid chromatography? What types of analytes and samples can you use LC for? Who is this course for? This course is ideal either as stand-alone or prior to attending the Practical Essentials of HPLC & LC-MS, Complete HPLC & LC-MS, Hands-on HPLC & LC-MS or one of our manufacturer-specific Comprehensive courses.
This course is an introduction to mass spectral interpretation, aimed at presenting the fundamental tools and rules when examining high quality full-scan GC-MS data. Every analyst using GC-MS should have a fundamental understanding of how a mass spectrum is generated and if a library match is correct or not. From learning to quickly recognise from the spectrum if the analyte is aliphatic or aromatic in nature; to learning to interpret the number of carbon atoms, heteroatoms and degree of unsaturation; and understand isotopes, isomers, logical losses, cleavages and rearrangements to produce a mass spectral fingerprint of the compound. The course is classroom based and combines powerpoint presentations to introduce the theory with a high proportion of exercises on spectral data to reinforce the topics learned. Who is this course for? This course is recommended for those who have a good background in chemistry and at least six months experience as a GC-MS operator.
This course teaches you the theory of deconvolution, how to use and optimise it to find co-eluting peaks and peaks below the baseline in your GC-MS data, through presentations and demonstrations using deconvolution software by the course instructor. Learning outcomes You will learn about analytical resolution in mass spectrometry You will learn how deconvolution works and have demonstrations using deconvolution software You will learn the benefits of using deconvolution for processing GC-MS data Who is this course for? Beginners Analysts, Data Analysts or Technicians Lab Managers and Line Managers Report Writers Service Engineers and Consultant Engineers Those involved in the Sales or Marketing of the software or the technique for sample data analysis If you need to understand how deconvolution works and how it will benefit your GC-MS data analysis, then come along and learn from this course. This course is for someone who has some knowledge of GC-MS.
The Comprehensive ICP-MS Software Training course introduces the Agilent MassHunter software for instrument control, data acquisition and data analysis focusing on single quadrupole ICP-MS. The course covers PC and data system set-up and maintenance; an overview of MassHunter software; tuning methods; creating batches, methods and sequences; quantitative data analysis and reports It combines a mixture of presentations with software exercises, to give you comprehensive training. Who is this course for? This course is primarily for analysts and technicians responsible for the operation of Agilent single quadrupole ICP-MS instruments and data analysis using MassHunter software.
This module is a perfect introduction for absolute beginners to Thermal Gravimetric Analysis (TGA), Differential Scanning Calorimetry (DSC), Karl Fischer Titration (KF) and Powder X-ray Diffraction (PXRD). The course will cover the what, why, where, when and how of each techniques. Who is this course for? Beginners Analysts or Technicians looking for a refresher in these techniques. Lab Managers and Line Managers – those who are responsible for the instruments or the analysts using them. Data Analysts and Report Writers – technical specialists who aren’t using the instruments but are using data from them. Service Engineers and Consultant Engineers – those who look after or recommend the use of these instruments but don’t have the chemistry background or chemistry viewpoint. Those involved in the Sales or Marketing of these instruments, their consumables or their use for analysis – e.g. manufacturers, contract labs, media companies.
The Complete GC & GC-MS course is built from the Practical Essentials of GC & GC-MS and the GC & GC-MS Clinic courses to provide a complete training solution enabling you to understand your Gas Chromatograph or GC-MS instrument, develop applications, troubleshoot & maintain it. This course covers all the practical theory you need to know about Gas Chromatography and its related techniques including gas chromatography-mass spectrometry; gases and plumbing; sample introduction like split, splitless, on-column and large volume injection techniques; data analysis; and sampling techniques like headspace, SPME, pyrolysis, thermal desorption, purge & trap, liquid-liquid and solid-phase extraction. Who is this course for? The Complete GC & GC-MS course is for those who have some knowledge of gas chromatography and would like to greatly enhance it, learning the essential and practical theory about all available GC & GC-MS techniques.
This course teaches the fundamentals of gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Attendees will gain a firm foundation in these techniques by learning about the instrumentation used, how the separation process occurs and gaining an overview of the function and operation of each component of the instrument. The types of samples which can be analysed are covered, along with the different sampling techniques available and considerations when preparing samples. Beyond the instrumentation, the course discusses why the technique is used and the answers it can give, looking at qualitative and quantitative data analysis, to give you a full picture. Who is this course for? This course is ideal either as stand-alone or prior to attending the Practical Essentials of GC & GC-MS, Complete GC & GC-MS, Hands-on GC & GC-MS or one of our manufacturer-specific Comprehensive courses.
This is a perfect introduction for absolute beginners to ICP. The course will cover the what, how, why, when and where of ICP-OES & ICP-MS. What is inductively coupled plasma – optical emission spectroscopy (ICP-OES) & mass spectrometry (ICP-MS)? How does ICP-OES and ICP-MS work? What instrumentation is available? Why do we use ICP-OES and ICP-MS? How could it help solve problems and what answers could it give? When do we use ICP-OES and ICP-MS? Which applications to answer what questions? Where do we use ICP-OES and ICP-MS? Who is this course for? Beginners Analysts or Technicians Lab Managers and Line Managers Data Analysts and Report Writers Service Engineers and Consultant Engineers Those involved in the Sales or Marketing of these instruments, their consumables or their use for analysis
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What will you learn on this course? This one day classroom based course teaches you the theory of how to use this powerful Automated Mass Spectral Deconvolution and Identification System software to process your GC-MS data through presentations and demonstrations by the course instructor. Who is this course for? If you need to understand how deconvolution works with the AMDIS software, then come along and learn from this course. This course is for someone who has fundamental knowledge of GC-MS.
What will you learn on this course? This one day course will cover the fundamentals of the Agilent Deconvolution Reporting Software, which is an additional application package to the Agilent GC-MSD Chemstation software and combines the results from the MSD Chemstation, AMDIS and the NIST search engine into a single report. This course will take you through the individual steps to create your own DRS libraries; from creating a retention time locked GC-MS method in MSD Chemstation which produces high quality data; to creating a MSD Chemstation user library which is then converted to a quantitation database and an AMDIS library; to optimising AMDIS settings; creating a DRS method to control the 3 pieces of software; and finally generate and interpret a report. The final part of the course is learning how to maintain and troubleshoot the DRS method, including where to add new compounds. Those attending the DRS course will receive a FREE poster on the DRS guide taught throughout the cour
An introduction to mass spectral interpretation, aimed at presenting the fundamental tools and rules when examining high quality full-scan GC-MS data. Every analyst using GC-MS should have a fundamental understanding of how a mass spectrum is generated and if a library match is correct or not. This course takes this a step further to enhance mass spectral knowledge. From learning to quickly recognise from the spectrum if the analyte is aliphatic or aromatic in nature; to learning to interpret the number of carbon atoms, heteroatoms and degree of unsaturation; and understand isotopes, isomers, logical losses, cleavages and rearrangements to produce a mass spectral fingerprint of the compound. The course is classroom based and combines powerpoint presentations to introduce the theory with a high proportion of exercises on spectral data to reinforce the topics learned. If you wish to learn the fundamentals of mass spectral interpretation for the identification of unknowns or to enhance th
The Hands-On Sample Preparation course combines the 4 individual hands-on sample preparation days covering Headspace, Solid-Phase Micro-Extraction (SPME), Thermal Desorption (TD) and Pyrolysis. These courses will teach you the theory for each sample preparation technique and you will perform practical exercises to use this knowledge to create methods, analyse samples and experiment with parameters. These courses have a 50:50 mix of theory and hands-on practicals in a laboratory environment.
What will you learn on this course? Spend the first day learning the theory of mass-spectrometry and then use this knowledge to create GC-MS methods, perform injections and change MS parameters to see the effects. The final day combines learning the reasons why maintenance is required, what happens if maintenance isn’t performed and the signs of when maintenance is needed along with practicals carrying out maintenance on mass spectrometers. This course will cover MSD theory, methods and maintenance of a GC-quadrupole-MS. Who is this course for? This course is suitable for those with some knowledge of GC. Please note: this course will only cover the MSD not the GC, refer to the ‘GC’ courses for training on that part of the instrument.
This course looks at how to choose the GC & GC-MS techniques for an application, set-up the instrument, how to develop & optimise methods and then finally how to maintain & troubleshoot the instrument, techniques and method. This advanced course also takes a brief look at advanced techniques to help solve those very tricky or complex applications including Selective Discrimination, Deconvolution, Two-Dimensional GC (GC+GC & GCxGC) and Chemometrics.
This one day course is spent learning the theory of static and dynamic headspace and how to modify samples to improve results, then using this knowledge to create HS methods, analyse samples and experiment with parameters to see the effects. This course will cover static and dynamic headspace. Who is this course for? This course requires knowledge of GC or GC-MS.
This one day course is spent learning the theory behind Solid-Phase Micro-Extraction and how to modify samples to improve results, then using this knowledge to create SPME methods, analyse samples and experiment with parameters to see the effects. This course will cover Headspace-SPME and Immersion-SPME, SPME phases, SPME instrumentation & set up and troubleshooting. It will introduce related techniques like SBSE, SPE-TD and SPDE. Who is this course for? This course requires knowledge of GC or GC-MS.
This one day course begins with the theory of thermal desorption, types of samples that can be analysed using this technique, types of tube packing materials and how to collect samples. This knowledge is then used to create TD methods, collect and analyse samples and experiment with parameters to see the effects. This course will cover the thermal desorption of gas-phase and solid-phase samples. Who is this course for? This course requires knowledge of GC or GC-MS.
The four-day Comprehensive GC-MS Training course introduces the fundamental theory of quadrupole GC-MS along with the operation, maintenance and troubleshooting of the Agilent 5975 Mass Spectrometer using MSD Chemstation software. This course includes an introduction to quadrupole mass spectrometry; hardware configuration; MS tuning; data acquisition in scan and selected ion monitoring (SIM) modes; qualitative & quantitative data analysis; reports; sequencing; and an introduction to macros and retention time locking.