BRAVE Analytics products

Particle Analytics

BRAVE - OptoFluidic Force Induction for Particle Measurement in Research and Production

OptoFluidic Force Induction (OF2i®) is a patented technology designed for advanced nanoparticle characterization. Unlike conventional methods such as Dynamic Light Scattering (DLS) and Laser Diffraction, OF2i® enables continuous, real-time measurement of particle data, offering statistically significant insights into the entire particle population. Utilizing a donut-shaped vortex laser, it manipulates particles within a liquid sample, providing detailed analysis of particle size, distribution, and concentration. This method is applicable in diverse industries including pharmaceuticals, biotech, cosmetics, and environmental sciences. OF2i® offers products like BRAVE B-Continuous, an online PAT sensor for real-time process monitoring, and BRAVE B-Curious, a benchtop device for lab applications. The technology also integrates with Raman spectroscopy for detailed chemical analysis. By accelerating particles and minimizing Brownian motion effects, OF2i® ensures precise, representative measurement results, enhancing both research and production processes.

BRAVE - Analysis for Particle Characterization

BRAVE Analytics has developed a cutting-edge method for particle characterization by combining OptoFluidic Force Induction (OF2i) and Raman spectroscopy, inspired by Arthur Ashkin's optical tweezers. The technique uses light's ability to manipulate and trap particles, facilitating the measurement of particle size, concentration, and chemical composition in a continuous flow system. The BRAVE B-Elementary module features an innovative setup that slows down or stops particles momentarily to read their Raman spectra, achieving high-throughput analysis of up to 60 particles per minute. This user-friendly system requires minimal sample preparation and can process a wide range of particle sizes from approximately 500 nm to 5 µm. It can be enriched by integrating inductively coupled plasma-time-of-flight mass spectrometry (ICP-ToF-MS) for complementary analysis, delivering highly sensitive measurements even at ultra-low particle concentrations. Potential applications span from nanotoxicology and quality control in pharmaceuticals to environmental science, enabling detailed, accurate particle characterization.