Cerno Bioscience is dedicated to the practical application of modern mathematical techniques to Mass Spectrometry for the purpose of improving the quality, accuracy, and reliability of MS analysis. Founded and staffed by a team with many years of experience in the fields of instrumentation, mathematical data processing, analytical software research and development and real world applications to problem solving, Cerno Bioscience is uniquely positioned to provide significant improvements to all types of MS experiment and applications. Cerno develops and publishes award-winning mass spectrometry calibration and analysis software which not only enables formula determination at unit mass resolution (single or triple quad) with 100x improvement in mass accuracy (CLIPS), a capability typically reserved only for HiRes MS systems, but also improves formula ID at HiRes by 20x through the Spectral Accuracy concept (sCLIPS).
Cerno Bioscience has developed unique, patented technologies that can expand, enhance and greatly extend the utility of mass spectrometry in a number of established and evolving application areas ranging from impurity identification, contaminant analysis, de-formulation, process development, natural product chemistry, organic synthesis, labelled isotope analysis, metabolomics to biologics modification, identification and proteomics, both for qualitative as well as quantitative analysis. The technologies developed by Cerno Bioscience dramatically improve the amount of information obtainable from, and reduce the amount of time required on, many MS experiments.
These dramatic results are enabled through the patented TrueCal™ calibration process and validated by hundreds of publications and thousands or satisfied users across the world.
For unit resolution quadrupoles:
- 100x better mass accuracy
- up to 99.9% Spectral Accuracy
- Confident elemental composition determination
- Mixture deconvolution for isotope analysis and large molecule degredation
For high resolution TOF, Orbitrap, FT ICR:
- Self-calibrates peak shape without standards for exact isotope modeling
- Eliminates 95-99% of incorrect formulas with high spectral accuracy
- Quantitative measurements for biologics degradation analysis