Cerno Bioscience products

TrueCal truly makes your mass spec data as perfect or ideal as what is ultimately possible in the physical sense. 

TrueFit MX™ allows the spectral deconvolution of chromatographically unresolved compounds commonly encountered in labeled isotope work, protein or oligonucleotide modifications, electron impact MS, or even for the direct analysis of complex mixtures.

While TrueFit MX provides spectral deconvolution of mixtures considering proposed compounds, TrueChrom MX™ automatically detects the presence of chromatographically unresolved peaks and determines the number of components in the unresolved peak.  TrueFit MX then uses its patent pending deconvolution algorithm to calculate the pure component spectra of each of the components.  The pure component spectra can then be analyzed by library search to determine the identity each compound from the unresolved chromatographic peak.

CLIPS (Calibrated Line-shape Isotope Profile Search) is an entirely new and revolutionary way to attain fast and reliable elemental composition determination. Elemental composition is determined using the accurate mass information to identify a list of formula candidates. But even with very high mass accuracy, the list of formula candidates can make unambiguous formula determination difficult.

sCLIPS (self Calibrating Line-shape Isotope Profile Search) enables users of accurate mass instruments including TOF, high resolution quadrupoles, Orbitrap, magnetic sector, and FT-ICR MS to dramatically improve formula ID through Spectral Accuracy without the need to run calibration standards.  The patented sCLIPS approach utilizes the fully resolved monoisotopic peak from high resolution instruments to create a line-shape TrueCal™ calibration that is applied to the entire isotope profile of the ion of interest.