Cornell Scientific Instruments Pvt. Ltd. products

With Monolith X, you’ll get Spectral Shift and MST — two biophysical modalities to help cover all the types of interactions you encounter. You’ll enjoy high-quality results without spending your time on assay development and finally perform experiments without worrying about sample aggregation or impurities.

PROMETHEUS PANTA represents a comprehensive solution for protein stability characterization, offering multi-parameter data on conformational and colloidal stability. Designed to reveal liabilities or stability enhancements that other technologies might miss, this instrument allows for the measurement of thermal stability, aggregation, and particle sizing and dispersity within a single run, without the need for labels or large sample sizes. It provides reliable, high-resolution data useful in evaluating protein stability, making it optimal for challenging stability characterization tasks. Employing technologies such as nanoDSF, DLS, backreflection, and SLS, PROMETHEUS PANTA presents a diverse array of information pertaining to thermal unfolding, particle sizing, and aggregation. This unified approach in a single instrument facilitates a thorough understanding of stability, catering to a variety of applications without using labeled candidates.

The Rescan Confocal Microscope (RCM) from Cornell Scientific Instruments Pvt. Ltd. offers an advanced imaging system that employs a unique dual scanning mirror architecture. This architecture, consisting of a scanning mirror set and a re-scanning mirror set, allows for scanning the specimen and concurrently writing the emission signal onto a camera chip. This dual scanning process not only enhances image resolution but also forgoes any need for post-processing. The RCM system supports a standard C-mount interface for seamless integration with microscopes and cameras. Its opto-mechanical basis ensures that increased lateral resolution, from 240nm to 170nm, is achieved without relying on computational enhancements. Additionally, the re-scanned emission significantly boosts the signal-to-noise ratio by four times compared to conventional confocal microscopes. The passive enhancement in photon efficiency results in minimal photo-toxicity, making it suitable for detailed biomedical imaging applications. The open pinhole configuration (AU=2) and deeper confocality provide superior image quality, highlighting the RCM's capability for high-resolution, low-noise microscopy.

The Aurox Clarity Laser Free Confocal (LFC) is an advanced imaging device designed to transform virtually any laboratory microscope into a confocal microscope. Its laser-free operation ensures high-quality imaging without the complexity and costs associated with traditional laser-based systems. The compact, patented optical design allows for straightforward retrofitting to existing fluorescence microscopes and can easily be integrated into most new microscope models. By providing an affordable, in-house confocal microscopy solution, the Aurox Clarity LFC eliminates the necessity of accessing core facility equipment. This makes it a valuable addition to research laboratories aiming to enhance their imaging capabilities while maintaining cost-effectiveness.