28 services found

Creative Biogene services

Oligonucleotide Synthesis Services

The oligos have been applied in almost all fields of molecular biology, and have become the top choice for researchers. Creative Biogene provides a full spectrum of high quality specialty oligonucleotide synthesis service that range from oligo synthesis for both research and cGMP grade, oligonucleotide modifications to high throughput DNA, RNA oligo synthesis.Our custom DNA oligos are optimized for various synthesis scales, modifications and applications to ensure consistently high quality and fast turnaround time.

creative biogene - GFP Reporter Stable Cell Line

The green fluorescent protein (GFP) is a protein composed of 238 amino acid residues (26.9kDa) that exhibits bright green fluorescence when exposed to light in the blue to ultraviolet range. Although many other marine organisms have similar green fluorescent proteins, GFP traditionally refers to the protein first isolated from the jellyfish Aequorea victoria. The GFP from A. victoria has a major excitation peak at a wavelength of 395 nm and a minor one at 475 nm. Its emission peak is at 509 nm, which is in the lower green portion of the visible spectrum. The fluorescence quantum yield (QY) of GFP is 0.79. The GFP from the sea pansy (Renilla reniformis) has a single major excitation peak at 498 nm.

Microbialtec - Microbial Fermentation

Microbial fermentation processes have been manipulated by humans and are used extensively in the production of various foods and other commercial products, including pharmaceuticals. Microbial fermentation can also be useful for identifying microbes for diagnostic purposes. Several fermentation products are important commercially outside of the food industry. For example, chemical solvents such as acetone and butanol are produced during acetone-butanol-ethanol fermentation. Complex organic pharmaceutical compounds used in antibiotics, vaccines, and vitamins are produced through mixed acid fermentation.

creative biogene - LncRNA qPCR

Long non-coding RNAs (lncRNAs) are non-coding transcripts longer than 200 nucleotides. Most of long non-coding RNAs (lncRNAs) are poorly annotated. Recent recognition about lncRNAs high lights their effects in many biological and pathological processes. The recent research shown that they have several functions involved in many cellular mechanisms, including signaling pathways regulation, activation and repression of transcription, chromatin structure regulation and post transcriptomic regulation. The dysfunction of LncRNAs is associated with a variety of human diseases varying from cancerous to non-cancerous diseases. Thus, characterization of these lncRNA genes and their modes of action may allow their use for diagnosis, monitoring of progression and targeted therapies in various diseases.

creative biogene - crispr cas9 vector

Homology repair (HDR) is a natural DNA repair mechanism induced by DNA double-strand breaks (DSB). The CRISPR/Cas9 system generates DSB on the chromosome, resulting in DNA repair. In the presence of donor DNA, homologous directed repair (HDR) occurs and replaces the genetic information (insertion, removal or substitution) in the chromosome with new information from the donor DNA. crispr cas9 vector

creative biogene - characterization testing

Creative Biogene has gathered a number of senior experts to provide the molecular characterization testing service to clients with stable quality and reasonable price. Creative Biogene is based on the frontiers of transgenic plant service with complete transformation system and years of service experience. And we have mature screening and testing technology for transgenic plants.

creative biogene - Rosa26 Knockin Mouse

The Rosa26 locus on mouse chromosome 6 is often used to integrate transgenic structures to achieve ubiquitous or conditional gene expression in mice and is considered to be one of the ideal locations for knockin targeted genes. The DNA fragments placed at the Rosa26 site are very safe and stable. Using the classical gene targeting method, obtain a gene knockin mouse at Rosa26 always takes one year or more. With the application of CRISPR/Cas9-mediated knockin technology, large DNA fragments can be accurately and efficiently inserted into the Rosa26.

creative biogene - antisense oligonucleotide companies

Creative Biogene is one of the leading biotechnology companies which has the expertise and ability in providing antisense oligonucleotide service for customers worldwide. Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to provide you with the comprehensive antisense oligonucleotide service, including antisense oligonucleotide synthesis, ASO in vitro screening service and ASO in vivo testing service. Creative Biogene’s goal is to provide you with the most affordable, high-quality antisense oligonucleotide service to ensure your satisfaction in a timely and professional manner.

creative biogene - Cell Bank Characterization

Creative Biogene provides a comprehensive cell bank characterization service for customers to ensure the biosafety and control of biological and biotechnological products. Based on leading-edge facilities and excellent platform, our experienced staff offer a wide range of assays to character cell bank according to ICH guideline Q5D. At Creative Biogene, we perform cell bank characterization services for different needs, including master cell bank, working cell bank and end of production cell bank. Reliable, rapid and accurate results will be delivered to assist customers to assess the quality of cell banks.

creative biogene - Plant Expression Vector Construction

Creative Biogene is an expert in plant genetic engineering and molecular biology. We have devoted many years of efforts in optimizing plant expression vectors to adapt to different plant species. We provide universal and customized plant expression vector construction services, covering from sequence optimization, gene synthesis/cloning, DNA fragment assembling, sequencing to plasmid preparation. With advanced technologies and highly experienced staffs, we will work closely with you to bring satisfied plant expression vector construction services.