Dikma Technologies Inc. products

Ultra fast separation without compromising resolution. Compatible with all HPLC and UHPLC instruments. Method development flexibility. Wide pH stability. Outstanding selectivity.

HILIC is normal phase chromatography of polar and ionic compounds under RP conditions. It combines the characteristics of three methods in LC – RP, NP, and IC. Inspire HILIC columns retain a water-enriched layer on the surface of the silica. This water layer facilitates the transfer of polar compounds onto the stationary phase for increased retention. Separation is achieved through the partitioning of polar solutes from the high concentration, water-miscible, organic mobile phase into the hydrophilic surface environment. Polar solutes exhibit increased retention, and elute in the order of increasing hydrophilicity. HILIC is ideal for separating and retaining polar compounds that may not retain on traditional RP packings. Unlike reversed-phase columns, Inspire HILIC columns retain highly polar compounds with only small amounts of water in the mobile phase. These more volatile mobile phases increase sensitivity with microbore applications.

Spursil polar-modified phases are based on ultra high-purity silica and novel polar modification technology. The unique bonded phases maximize polar retention and selectivity, while virtually eliminating silanol activity. The resulting polar-modified packing material contains a surface which is easily `wetted` with polar eluents and can run in highly aqueous conditions. The polar group also seems to play a role in base deactivation. We have seen some evidence that hydrogen bonding occurs between certain polar linkers and the silica surface, thereby decreasing the interaction of such silanols with basic components in the sample. Additionally, polar-modified phases often provide selectivity quite different from standard C18 phases.

Bio-Bond columns with 300 Å pore silica gel are suitable for analysis of proteins, peptides and biological samples. Meticulous care is given to the quality control of surface smoothness, particle shape, pore structure and pore consistency to ensure uniformity of particle structure and enhanced mechanical strength. A low fine percentage from damaged silica particles strengthens the column bed, leading to low backpressure and enhanced column performance and lifetime. Ultra low active silanol and metal content make perfect symmetrical peaks and avoid protein absorption, thereby ensuring detectable activity for protein sensitive to metal.

Platisil NH2 columns retain hydrogen-bonding compounds under three separation modes – RP, NP, and IC. Platisil NH2 columns provide reproducible retention and selectivity with improved column lifetime.

Features of EasyGuard Columns: Universal design to match any brand column. A variety of optional bonded phase material. Does not affect the analytical column resolution. Long lifetime column cartridges, high performance and low price.

Inspire material meets the most stringent requirements from analytical to preparative scale in the pharmaceutical industry. High surface area and carbon load are the keys to success. These features meet preparative chromatography resolution, and loadability requirements in the pharmaceutical production.

Guard Column / Transfer Lines (Intermediate Polarity Deactivated): Use in a wide variety of applications. Allow most common solvents.

100% Dimethyl polysiloxane. General purpose column of non-polar phase. Long lifetime. Temperature range: -60 ºC to 350 ºC. Bonded and cross-linked phase, solvent rinsable. DM-1MS is a low bleed column, use for MSDs. Similar to DB-1, SPB-1, HP-1, etc. Equivalent to USP G1, G2, G38 phases.