FISBA products

Optical microscopy has been a foundational instrument platform for understanding biological life since the pioneering cell imaging work conducted by Robert Hooke in the 17th century. It has grown from a primary research tool based on standard platform architectures and evolved into a highly specialized piece of equipment.  It is ubiquitous across life science research, from DNA-sequencing to super-resolution imaging of proteins inside cells and used by drug developers to explore and understand the function and behavior of biomolecules and edits cells as they screen for new pharmaceutical drugs by imaging and analyzing.  

Recent advances in biotechnology and sub-cellular imaging instrumentation have led to discoveries in fundamental life science biology and aided new developments in precision medicine. With the combination of fluorescence-based DNA-sequencing and super-resolution microscopy, it is now possible to image the location of individual biomolecules (e.g., proteins, mRNA) and understand how they behave and interact in the cellular environment with sub-100 nm resolution. This new technology frontier in life science research is known as Spatial Sequencing or Spatial Omics. By adding spatial resolution to the molecular information (gene profiling), this technology platform creates an unparalleled understanding of the relationship between an individual cell’s genomic (transcriptomic) profile, cellular morphology, and interaction with the local environment.